Browsing by Subject "Tautomer"
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DNA Conformational Equilibria in Replication Fidelity
(2019)All organisms must accurately replicate their genomic DNA in order to transmit genetic information from generation to generation. The cognate Watson-Crick base pairs (dA•dT, dG•dC) adopt near identical ‘Watson-Crick geometry’ ... -
Visualizing Rare Watson-Crick-Like Tautomeric and Anionic Mismatches in DNA and RNA
(2016)The central dogma of molecular biology relies on the correct Watson-Crick (WC) geometry of canonical deoxyribonucleic acid (DNA) dG•dC and dA•dT base pairs to replicate and transcribe genetic information with speed and an ...