Browsing by Subject "Transcription Factor"
Now showing items 1-4 of 4
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Engineering Transcription Factors to Program Cell Fate Decisions
(2015)Technologies for engineering new functions into proteins are advancing biological research, biotechnology, and medicine at an astounding rate. Building on fundamental research of natural protein structure and function, scientists ... -
K-mer Based Methods for Measuring and Predicting DNA-Binding Specificity of Transcription Factors
(2023)Transcription factors (TFs) are proteins that bind DNA based on the sequence and structure to regulate gene expression. They are fundamental components of genomic function, present in all known forms of life. Thus, understanding ... -
Novel Protein Regulators of Heat Shock Transcription Factor 1 During Stress and Disease
(2019)Heat Shock Transcription Factor 1 (HSF1) is a critical regulator of transcription that facilitates cellular stress protection in response to protein misfolding, rapid cell proliferation, and other stressful conditions. Defective ... -
Systematic Examination of Epigenomic Regulation of Neuronal Plasticity
(2022)The epigenome underlies cell type and state and in post-mitotic neurons, and it regulates the ability for rapid response to activity. Since neurons exit the cell cycle early in development and are long lived, remodeling ...
