Browsing by Subject "Transcription factors"
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Deciphering the Quantitative Effects of Cooperativity and Mutations on Transcription Factor Binding
(2022)Transcription factor (TF) proteins bind to DNA in a sequence specific manner to regulate gene expression. The binding affinity of TFs for individual sites is well characterized and can be represented using DNA motif models ... -
Modeling Multi-factor Binding of the Genome
(2010)Hundreds of different factors adorn the eukaryotic genome, binding to it in large number. These DNA binding factors (DBFs) include nucleosomes, transcription factors (TFs), and other proteins and protein complexes, such ... -
Transcription Factors as Competitors in Gene Regulation and DNA Damage Repair
(2022)Transcription factors (TFs) bind genomic DNA to regulate gene expression. In the cell, the genome is decorated with numerous proteins, including nucleosomes and proteins involved in processes such as DNA repair and replication, ...
