Now showing items 1-4 of 4

    • A decade of caspases. 

      Boyce, Michael; Degterev, Alexei; Yuan, Junying (Oncogene, 2003-11)
      Caspases are a family of cysteine proteases that play important roles in regulating apoptosis. A decade of research has generated a wealth of information on the signal transduction pathways mediated by caspases, the distinct ...
    • Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection. 

      Barki-Harrington, L; Chen, J; Le Corvoisier, P; Lefkowitz, Robert J; Lemaire, A; Naga Prasad, SV; Noma, T; ... (11 authors) (J Clin Invest, 2007-09)
      Deleterious effects on the heart from chronic stimulation of beta-adrenergic receptors (betaARs), members of the 7 transmembrane receptor family, have classically been shown to result from Gs-dependent adenylyl ...
    • For whom the bird sings: context-dependent gene expression. 

      Grossman, Matthew R; Jarvis, Erich David; Nottebohm, F; Ramos, JA; Scharff, C (Neuron, 1998-10)
      Male zebra finches display two song behaviors: directed and undirected singing. The two differ little in the vocalizations produced but greatly in how song is delivered. "Directed" song is usually accompanied by a courtship ...
    • Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation. 

      Bell, DA; Campbell, MR; Crawford, Gregory E; Safi, Alexias; Song, L; Su, D; Wang, X (PLoS Genet, 2015-01)
      Cellular stresses activate the tumor suppressor p53 protein leading to selective binding to DNA response elements (REs) and gene transactivation from a large pool of potential p53 REs (p53REs). To elucidate how p53RE sequences ...