Browsing by Subject "Trophoblasts"
Now showing items 1-3 of 3
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A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance.
(Science advances, 2016-03-04)In eutherians, the placenta acts as a barrier and conduit at the maternal-fetal interface. Syncytiotrophoblasts, the multinucleated cells that cover the placental villous tree surfaces of the human placenta, are directly ... -
Chromosome 19 microRNAs exert antiviral activity independent from type III interferon signaling.
(Placenta, 2018-01)INTRODUCTION:Cultured primary human trophoblasts (PHT), derived from term placentas, are relatively resistant to infection by diverse viruses. The resistance can be conferred to non-trophoblastic cells by pre-exposing them ... -
The Role of Congenital Cytomegalovirus Infection in Adverse Birth Outcomes: A Review of the Potential Mechanisms.
(Viruses, 2020-12-24)Human cytomegalovirus (CMV) is a major cause of nonhereditary adverse birth outcomes, including hearing and visual loss, neurologic deficits, and intrauterine growth retardation (IUGR), and may contribute to outcomes such ...
