Browsing by Subject "UNFOLDED PROTEIN RESPONSE"
Now showing items 1-2 of 2
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Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection.
(Scientific reports, 2016-09-27)On Earth, biological systems have evolved in response to environmental stressors, interactions dictated by physical forces that include gravity. The absence of gravity is an extreme stressor and the impact of its absence ... -
Oxidative stress promotes SIRT1 recruitment to the GADD34/PP1α complex to activate its deacetylase function.
(Cell death and differentiation, 2018-02)Phosphorylation of the eukaryotic translation initiation factor, eIF2α, by stress-activated protein kinases and dephosphorylation by the growth arrest and DNA damage-inducible protein (GADD34)-containing phosphatase is a ...