Browsing by Subject "Vaccination"
Now showing items 1-18 of 18
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Adenovirus F protein as a delivery vehicle for botulinum B.
(BMC Immunol, 2010-07-07)BACKGROUND: Immunization with recombinant carboxyl-terminal domain of the heavy chain (Hc domain) of botulinum neurotoxin (BoNT) stimulates protective immunity against native BoNT challenge. Most studies developing a botulism ... -
Capacity Assessment and Planning of COVID-19-Vaccination Sites: A Mathematical and Simulation Approach
(2022)Background: To control and minimize the spread of COVID-19, vaccination among the population to achieve herd immunity is important. However, optimizing the vaccination capacity for facility-based vaccination sites and mass ... -
CD20 deficiency in humans results in impaired T cell-independent antibody responses.
(J Clin Invest, 2010-01)CD20 was the first B cell differentiation antigen identified, and CD20-specific mAbs are commonly used for the treatment of B cell malignancies and autoantibody-mediated autoimmune diseases. Despite this the role of CD20 ... -
Immune checkpoint modulation enhances HIV-1 antibody induction.
(Nature communications, 2020-02-19)Eliciting protective titers of HIV-1 broadly neutralizing antibodies (bnAbs) is a goal of HIV-1 vaccine development, but current vaccine strategies have yet to induce bnAbs in humans. Many bnAbs isolated from HIV-1-infected ... -
Impact of Bacillus Calmette-Guérin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 infection.
(BJS open, 2021-11)<jats:p>There is little evidence around the potentially protective role of previous Bacillus Calmette-Guerin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 vaccination. Prior ... -
Influenza Vaccination Implementation and Timing for Sri Lanka: A Cost-Effectiveness Analysis
(2021)Influenza causes an estimated 3 to 5 million cases of severe illness annually, along with substantial morbidity and mortality, particularly among low and middle-income countries (LMICs). The most effective way to decrease ... -
Influenza vaccination of household contacts of newborns: a hospital-based strategy to increase vaccination rates.
(Infect Control Hosp Epidemiol, 2010-10)We implemented a hospital-based influenza vaccination program for household contacts of newborns. Among mothers not vaccinated prenatally, 44.7% were vaccinated through the program, as were 25.7% of fathers. A hospital-based ... -
Maternal Effects of Respiratory Syncytial Virus Infection during Pregnancy.
(Emerg Infect Dis, 2015-11)Given the illness and deaths caused by respiratory syncytial virus (RSV) infection during the first year of life, preventing infant RSV infections through maternal vaccination is intriguing. However, little is known about ... -
Navigating the devious course of evolution: the importance of mechanistic models for identifying eco-evolutionary dynamics in nature.
(Am Nat, 2013-05)In proposing his genetic feedback mechanism, David Pimentel was one of the first biologists to argue that the reciprocal interplay of ecological and evolutionary dynamics is an important process regulating population dynamics ... -
Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses.
(Nature, 2021-06)Betacoronaviruses caused the outbreaks of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome, as well as the current pandemic of SARS coronavirus 2 (SARS-CoV-2)1-4. Vaccines that elicit protective ... -
Phenotypic and functional profile of HIV-inhibitory CD8 T cells elicited by natural infection and heterologous prime/boost vaccination.
(Journal of virology, 2010-05)Control of HIV-1 replication following nonsterilizing HIV-1 vaccination could be achieved by vaccine-elicited CD8(+) T-cell-mediated antiviral activity. To date, neither the functional nor the phenotypic profiles of CD8(+) ... -
Potent functional antibody responses elicited by HIV-I DNA priming and boosting with heterologous HIV-1 recombinant MVA in healthy Tanzanian adults.
(PLoS One, 2015)UNLABELLED: Vaccine-induced HIV antibodies were evaluated in serum samples collected from healthy Tanzanian volunteers participating in a phase I/II placebo-controlled double blind trial using multi-clade, multigene HIV-DNA ... -
Potential To Streamline Heterologous DNA Prime and NYVAC/Protein Boost HIV Vaccine Regimens in Rhesus Macaques by Employing Improved Antigens.
(J Virol, 2016-04)UNLABELLED: In a follow-up to the modest efficacy observed in the RV144 trial, researchers in the HIV vaccine field seek to substantiate and extend the results by evaluating other poxvirus vectors and combinations with DNA ... -
Relational Mobility Predicts Faster Spread of COVID-19: A 39-Country Study.
(Psychological science, 2020-10)It has become increasingly clear that COVID-19 is transmitted between individuals. It stands to reason that the spread of the virus depends on sociocultural ecologies that facilitate or inhibit social contact. In particular, ... -
Stabilized HIV-1 envelope immunization induces neutralizing antibodies to the CD4bs and protects macaques against mucosal infection.
(Science translational medicine, 2022-09)A successful HIV-1 vaccine will require induction of a polyclonal neutralizing antibody (nAb) response, yet vaccine-mediated induction of such a response in primates remains a challenge. We found that a stabilized HIV-1 ... -
The Timeliness of Childhood Vaccinations in Tanzania: A Literature Review and Analysis of Demographic Health Surveys Data
(2017)Background: Routine immunization is the most effective way to prevent mortality from vaccine preventable diseases. Though vaccination coverage rates have improved over the past decade, vaccinations still fail to be delivered ... -
Travelers with sickle cell disease.
(J Travel Med, 2014-09)BACKGROUND: Sickle cell disease (SCD) is the most common genetic disease among persons with African ancestry. This article provides a background to SCD and reviews many important aspects of travel preparation in this population. ... -
Veterans health administration hepatitis B testing and treatment with anti-CD20 antibody administration.
(World J Gastroenterol, 2016-05-21)AIM: To evaluate pretreatment hepatitis B virus (HBV) testing, vaccination, and antiviral treatment rates in Veterans Affairs patients receiving anti-CD20 Ab for quality improvement. METHODS: We performed a retrospective ...
