Browsing by Subject "Vaccine"
Now showing items 1-8 of 8
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Characterizing Bladder Adaptive Immune Responses to Uropathogenic Escherichia coli Infections
(2012)The mammalian urinary bladder is a highly specialized organ that must be able to withstand considerable amounts of osmotic pressure at its mucosal surface, in addition to maintaining an impenetrable barrier against potential ... -
Evaluation of Vaccine‐induced Maternal Antibody Transfer and Impact on Infant Immune Responses in the Rabbit Model
(2019)Maternal vaccination protects infants through transplacental transfer of vaccine-specific maternal IgG and milk transfer of IgG and IgA antibodies from mother to child. I performed experiments in the rabbit model, which ... -
Examining Mycobacterial Interactions with Host Cellular Pathways
(2015)Tuberculosis is a devastating disease that has been plaguing humankind for millennia. Co-evolution of humans with Mycobacterium tuberculosis, the causative agent of the disease, has allowed for the pathogen to possess an ... -
Global Equity Challenges in COVID-19 Vaccine Purchasing
(2021-04-21)A rush to preemptively secure COVID-19 vaccines resulted in high income countries hoarding an excess supply while low- and middle-income countries are prevented from equitable access. Previous work on equity in vaccine purchasing ... -
Molecular and Macroscale Engineering of Sublingual Nanofiber Vaccines
(2020)Short peptides are poorly immunogenic when delivered sublingually – under the tongue. This challenge has prevented widespread investigation into sublingual peptide vaccines, leaving their considerable potential untapped. ... -
The Center for HIV/AIDS Vaccine Immunology (CHAVI) multi-site quality assurance program for cryopreserved human peripheral blood mononuclear cells.
(J Immunol Methods, 2014-07)The Center for HIV/AIDS Vaccine Immunology (CHAVI) consortium was established to determine the host and virus factors associated with HIV transmission, infection and containment of virus replication, with the goal of advancing ... -
The Development and Mechanisms of Protective Humoral Immunity to HIV
(2018)A successful HIV-1 vaccine is likely to be comprised of a polyclonal response with multiple antiviral functions that generate both broadly neutralizing antibodies (bNAbs) that neutralize multiple strains of HIV and/ or functional ... -
The Development of Cancer Vaccines Targeting Neoantigens for the Treatment of Malignant Astrocytomas
(2018)Glioblastoma (GBM) is the most common malignant primary brain tumor in adults. Conventional therapies for GBM typically fail to provide lasting antitumor benefits, owing to their inability to specifically eliminate all malignant ...
