Now showing items 1-10 of 10

    • A refined model of the genomic basis for phenotypic variation in vertebrate hemostasis. 

      Ribeiro, Ângela M; Zepeda-Mendoza, M Lisandra; Bertelsen, Mads F; Kristensen, Annemarie T; Jarvis, Erich D; Gilbert, M Thomas P; da Fonseca, Rute R (BMC Evol Biol, 2015-06-30)
      BACKGROUND: Hemostasis is a defense mechanism that enhances an organism's survival by minimizing blood loss upon vascular injury. In vertebrates, hemostasis has been evolving with the cardio-vascular and hemodynamic systems ...
    • A unified anatomy ontology of the vertebrate skeletal system. 

      Dahdul, Wasila M; Balhoff, James P; Blackburn, David C; Diehl, Alexander D; Haendel, Melissa A; Hall, Brian K; Lapp, Hilmar; ... (15 authors) (PLoS One, 2012)
      The skeleton is of fundamental importance in research in comparative vertebrate morphology, paleontology, biomechanics, developmental biology, and systematics. Motivated by research questions that require computational access ...
    • Avian brains and a new understanding of vertebrate brain evolution. 

      Jarvis, Erich D; Güntürkün, Onur; Bruce, Laura; Csillag, András; Karten, Harvey; Kuenzel, Wayne; Medina, Loreta; ... (30 authors) (Nat Rev Neurosci, 2005-02)
      We believe that names have a powerful influence on the experiments we do and the way in which we think. For this reason, and in the light of new evidence about the function and evolution of the vertebrate brain, an international ...
    • Dynamic Glycosylation Governs the Vertebrate COPII Protein Trafficking Pathway. 

      Cox, Nathan J; Unlu, Gokhan; Bisnett, Brittany J; Meister, Thomas R; Condon, Brett M; Luo, Peter M; Smith, Timothy J; ... (13 authors) (Biochemistry, 2018-01)
      The COPII coat complex, which mediates secretory cargo trafficking from the endoplasmic reticulum, is a key control point for subcellular protein targeting. Because misdirected proteins cannot function, protein sorting by ...
    • Evidence for a single loss of mineralized teeth in the common avian ancestor. 

      Meredith, Robert W; Zhang, Guojie; Gilbert, M Thomas P; Jarvis, Erich D; Springer, Mark S (Science, 2014-12-12)
      Edentulism, the absence of teeth, has evolved convergently among vertebrates, including birds, turtles, and several lineages of mammals. Instead of teeth, modern birds (Neornithes) use a horny beak (rhamphotheca) and a muscular ...
    • Evolutionary genomics and adaptive evolution of the Hedgehog gene family (Shh, Ihh and Dhh) in vertebrates. 

      Pereira, Joana; Johnson, Warren E; O'Brien, Stephen J; Jarvis, Erich D; Zhang, Guojie; Gilbert, M Thomas P; Vasconcelos, Vitor; ... (8 authors) (PLoS One, 2014)
      The Hedgehog (Hh) gene family codes for a class of secreted proteins composed of two active domains that act as signalling molecules during embryo development, namely for the development of the nervous and skeletal systems ...
    • Intracellular Neural Recording with Pure Carbon Nanotube Probes. 

      Yoon, Inho; Hamaguchi, Kosuke; Borzenets, Ivan V; Finkelstein, Gleb; Mooney, Richard; Donald, Bruce R (PloS one, 2013-01)
      The computational complexity of the brain depends in part on a neuron's capacity to integrate electrochemical information from vast numbers of synaptic inputs. The measurements of synaptic activity that are crucial ...
    • Plant species' origin predicts dominance and response to nutrient enrichment and herbivores in global grasslands. 

      Seabloom, Eric W; Borer, Elizabeth T; Buckley, Yvonne M; Cleland, Elsa E; Davies, Kendi F; Firn, Jennifer; Harpole, W Stanley; ... (65 authors) (Nat Commun, 2015-07-15)
      Exotic species dominate many communities; however the functional significance of species' biogeographic origin remains highly contentious. This debate is fuelled in part by the lack of globally replicated, systematic data ...
    • Three periods of regulatory innovation during vertebrate evolution. 

      Lowe, Craig B; Kellis, Manolis; Siepel, Adam; Raney, Brian J; Clamp, Michele; Salama, Sofie R; Kingsley, David M; ... (9 authors) (Science (New York, N.Y.), 2011-08)
      The gain, loss, and modification of gene regulatory elements may underlie a substantial proportion of phenotypic changes on animal lineages. To investigate the gain of regulatory elements throughout vertebrate evolution, ...
    • Vertebrate herbivory impacts seedling recruitment more than niche partitioning or density-dependent mortality. 

      Clark, CJ; Poulsen, JR; Levey, DJ (Ecology, 2012-03)
      In tropical forests, resource-based niches and density-dependent mortality are mutually compatible mechanisms that can act simultaneously to limit seedling populations. Differences in the strengths of these mechanisms will ...