ALERT: This system is being upgraded on Tuesday December 12. It will not be available for use for several hours that day while the upgrade is in progress. Deposits to DukeSpace will be disabled on Monday December 11, so no new items are to be added to the repository while the upgrade is in progress. Everything should be back to normal by the end of day, December 12.

Browsing by Subject "Whole-Body Irradiation"

Now showing items 1-6 of 6

    • A translatable predictor of human radiation exposure. 

      Lucas, Joseph; Dressman, Holly K; Suchindran, Sunil; Nakamura, Mai; Chao, Nelson J; Himburg, Heather; Minor, Kerry; ... (12 authors) (PLoS One, 2014)
      Terrorism using radiological dirty bombs or improvised nuclear devices is recognized as a major threat to both public health and national security. In the event of a radiological or nuclear disaster, rapid and accurate ...

    • Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles. 

      Meadows, Sarah K; Dressman, Holly K; Daher, Pamela; Himburg, Heather; Russell, J Lauren; Doan, Phuong; Chao, Nelson J; ... (10 authors) (PLoS One, 2010-07-12)
      In the event of a terrorist-mediated attack in the United States using radiological or improvised nuclear weapons, it is expected that hundreds of thousands of people could be exposed to life-threatening levels of ionizing ...

    • Epidermal growth factor regulates hematopoietic regeneration after radiation injury. 

      Doan, Phuong L; Himburg, Heather A; Helms, Katherine; Russell, J Lauren; Fixsen, Emma; Quarmyne, Mamle; Harris, Jeffrey R; ... (12 authors) (Nat Med, 2013-03)
      The mechanisms that regulate hematopoietic stem cell (HSC) regeneration after myelosuppressive injury are not well understood. We identified epidermal growth factor (EGF) to be highly enriched in the bone marrow serum of ...

    • Gene expression signatures that predict radiation exposure in mice and humans. 

      Dressman, Holly K; Muramoto, Garrett G; Chao, Nelson J; Meadows, Sarah; Marshall, Dawn; Ginsburg, Geoffrey S; Nevins, Joseph R; ... (8 authors) (PLoS Med, 2007-04)
      BACKGROUND: The capacity to assess environmental inputs to biological phenotypes is limited by methods that can accurately and quantitatively measure these contributions. One such example can be seen in the context of exposure ...

    • Outcome of transplantation for acute lymphoblastic leukemia in children with Down syndrome. 

      Hitzler, Johann K; He, Wensheng; Doyle, John; Cairo, Mitchell; Camitta, Bruce M; Chan, Ka Wah; Diaz Perez, Miguel A; ... (21 authors) (Pediatric blood & cancer, 2014-06)
      We report on 27 patients with Down syndrome (DS) and acute lymphoblastic leukemia (ALL) who received allogeneic hematopoietic cell transplantation (HCT) between 2000 and 2009. Seventy-eight percent of patients received ...

    • Umbilical Cord Blood Transplantation in Children with Acute Leukemia: Impact of Conditioning on Transplantation Outcomes. 

      Eapen, Mary; Kurtzberg, Joanne; Zhang, Mei-Jie; Hattersely, Gareth; Fei, Mingwei; Mendizabal, Adam; Chan, Ka Wah; ... (12 authors) (Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017-10)
      The Blood and Marrow Transplant Clinical Trials Network (BMT CTN 0501) randomized children with hematologic malignancies to transplantation with 1 or 2 cord blood units (UCB) between 2006 and 2012. While the trial concluded ...