Browsing by Subject "Wnt"
Now showing items 1-5 of 5
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Activation of developmental signaling pathways in hematopoietic stem cell regeneration
(2010)The homeostatic hematopoietic stem cell compartment is comprised of quiescent long term self renewing stem cells and cycling short term stem cells with finite renewal potential. To study the molecular mechanisms governing ... -
Auxiliary Wnt3A Signaling in Cell Fate Decisions of C3H10T1/2 Mesenchymal Stem Cells
(2011)Activation of Wnt signaling pathways is critical to a variety of developmental events across all animal taxa. These highly evolutionarily conserved pathways are also important in the adult organism for maintaining homeostasis ... -
Regional Differences in Glioma: The Role of Pax3 in the Mechanisms and Cellular Origins of Brainstem Glioma
(2014)Brain tumors are an incredibly diverse group of neoplasms, as evidenced by their varied locations in the brain, histological characteristics, and genetic alterations. Brain tumor heterogeneity can be potentially explained ... -
SoxNeuro and Shavenbaby act cooperatively to shape denticles in the embryonic epidermis of Drosophila.
(Development, 2017-06-15)During development, extracellular signals are integrated by cells to induce the transcriptional circuitry that controls morphogenesis. In the fly epidermis, Wingless (Wg)/Wnt signaling directs cells to produce either a distinctly ... -
The Role of Secreted Frizzled Related Protein 3 (SFRP3) and the Wnt Signaling Pathway in PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma
(2015)Rhabdomyosarcoma is the most common pediatric soft tissue sarcoma and demonstrates features of skeletal muscle. Of the two predominant (pediatric) subtypes, embryonal (eRMS) and alveolar (aRMS), aRMS has the poorer prognosis, ...
