Browsing by Subject "actin"
Now showing items 1-8 of 8
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Cell Polarity Establishment in the Budding Yeast Saccharomyces Cerevisiae
(2009)Establishing an axis of cell polarity is central to cell motility, tissue morphogenesis, and cell proliferation. A highly conserved group of polarity regulators is responsible for organizing a wide variety of polarized ... -
Cytoskeletal Networks Driving Presynaptic Plasticity
(2021)Synapses – the delicate connections between our neurons – adjust and refine their strength to shape our brains, our thoughts, and our memories. Proteomic and genetic techniques have revealed that this process, known as synaptic ... -
Developmental mechanism of the periodic membrane skeleton in axons.
(Elife, 2014-12-23)Actin, spectrin, and associated molecules form a periodic sub-membrane lattice structure in axons. How this membrane skeleton is developed and why it preferentially forms in axons are unknown. Here, we studied the developmental ... -
Functional Analysis of the Cordon-bleu Protein in Mouse
(2009)The actin cytoskeleton is a fundamental component of the cell and is involved in many processes, including cell division, cell migration, vesicle trafficking and cell polarity. The actin cytoskeleton has a very important ... -
Identification of the Antifungal Metabolite Chaetoglobosin P From Discosia rubi Using a Cryptococcus neoformans Inhibition Assay: Insights Into Mode of Action and Biosynthesis.
(Frontiers in microbiology, 2020-01)Cryptococcus neoformans is an important human pathogen with limited options for treatments. We have interrogated extracts from fungal fermentations to find Cryptococcus-inhibiting natural products using assays for growth ... -
Novel Regulators of Actin Signaling During the Developmental Stage of Spine Formation and Maturation
(2018)Excitatory synapse formation during development involves the complex orchestration of both structural and functional alterations at the postsynaptic side, beginning with the formation of transient dendritic filopodia. ... -
Regulation of Morphogenetic Events in Saccharomyces cerevisiae
(2018)Tip growth in fungi involves highly polarized secretion and modification of the cell wall at the growing tip. The genetic requirements for initiating polarized growth are perhaps best understood for the model budding yeast, ... -
Understanding the Organization, Location, and Interactions of Actin-based Structures During Drosophila Dorsal Closure
(2018)Epithelial sheet morphogenesis is characterized by dynamic tissue movements, resulting in the recognition and adhesion of cells to generate a seamless epithelium. Each step is mediated by carefully organized, cellular actin ...
