Browsing by Subject "aneuploidy"
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Exploring the functional consequences of whole-genome duplication in tumor progression
(2021)Whole-genome duplication (WGD) generates polyploid cells possessing more than two copies of the genome. These events commonly occur during the evolution of human tumors across tissue types and mutational drivers, affecting ... -
Ordered structure of the transcription network inherited from the yeast whole-genome duplication
(2010)Background: Gene duplication, a major evolutionary path to genomic innovation, can occur at the scale of an entire genome. One such "whole-genome duplication" (WGD) event among the Ascomycota fungi gave rise to genes with ...