Browsing by Subject "bacteria"
Now showing items 1-16 of 16
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Analysis of the Transport Behavior of Escherichia Coli in a Novel Three-Dimensional In Vitro Tumor Model
(2010)Three-dimensional (3D) tumor models aim to reduce the need for animal models for drug and gene delivery studies. However, many models are not conducive to environmental manipulation and may not be easily adapted for <italic>in ... -
Assessing the Impacts of Silver Nanoparticles on the Growth, Diversity, and Function of Wastewater Bacteria
(2012)Silver nanoparticles (AgNPs) are increasingly being integrated into a wide range of consumer products, such as air filters, washing machines, and textiles, due to their antimicrobial properties [1]. However, despite the ... -
Assessing the well water quality in a rural Georgia county: Do Washington County citizens need to worry?
(2008-08-27)Under the Safe Drinking Water Act, public water sources must be monitored for contaminants; and the results are made public. However, this Act does not cover private wells, leaving a significant portion of the population ... -
Causes and consequences of microbial symbioses; insights from comparative genomics of plant associated bacterial-fungal interactions
(2017)Symbioses have shaped our modern world, providing for the air we breathe; for the plant and animal diversity we celebrate; and for the functioning of ecosystems from the tops of mountains to the ocean floor. Here I study ... -
Copper as an Antibacterial Agent and Disruptor of Protein Stability
(2020)The emergence of resistance to existing antibiotic drugs necessitates the development of new strategies to treat bacterial infections. Copper (Cu) has been used since ancient times to inhibit bacterial growth and has recently ... -
Ecological and Evolutionary Factors Shaping Animal-Bacterial Symbioses: Insights from Insects & Gut Symbionts
(2017)Animal bacterial symbioses are pervasive and underlie the success of many groups. Here, I study ecological and evolutionary factors that shape interactions between a host and gut associates. In this dissertation, I interrogate ... -
Exploring the Enzymology of Chlamydial Pathogenesis: An Investigation of Virulence and Energy Metabolism-Associated Enzymes
(2021)Chlamydia trachomatis is the obligate intracellular pathogen responsible for the most common bacterial sexually transmitted infection worldwide. While our front-line antibiotics have been historically successful in combatting ... -
How bacterial cell division might cheat turgor pressure - a unified mechanism of septal division in Gram-positive and Gram-negative bacteria.
(BioEssays : news and reviews in molecular, cellular and developmental biology, 2017-08)An important question for bacterial cell division is how the invaginating septum can overcome the turgor force generated by the high osmolarity of the cytoplasm. I suggest that it may not need to. Several studies in Gram-negative ... -
Lessons Learned from the Anaerobe Survey: Historical Perspective and Review of the Most Recent Data (2005-2007)
(2010)Background. The rationale and lessons learned through the evolution of the National Survey for the Susceptibility of Bacteroides fragilis Group from its initiation in 1981 through 2007 are reviewed here. The survey was conceived ... -
Nontuberculous mycobacterial infection after fractionated CO(2) laser resurfacing.
(Emerg Infect Dis, 2013-03)Nontuberculous mycobacteria are increasingly associated with cutaneous infections after cosmetic procedures. Fractionated CO2 resurfacing, a widely used technique for photorejuvenation, has been associated with a more favorable ... -
Q Fever, Scrub Typhus, and Rickettsial Diseases in Children, Kenya, 2011-2012.
(Emerg Infect Dis, 2016-05)To increase knowledge of undifferentiated fevers in Kenya, we tested paired serum samples from febrile children in western Kenya for antibodies against pathogens increasingly recognized to cause febrile illness in Africa. ... -
Reused Cultivation Water Accumulates Dissolved Organic Carbon and Uniquely Influences Different Marine Microalgae
(Frontiers in Bioengineering and Biotechnology, 2019-05-14) -
Targeting Drug-Resistant Bacteria with Metal-Binding Compounds for Antibacterial Activity and Metallo-β-Lactamase Inhibition
(2020)New strategies are urgently needed to overcome the growing threat of antibacterial drug resistance. One mechanism of drug resistance commonly employed by bacterial pathogens is expression of β-lactamases, which confer resistance ... -
The cell division protein MinD from Pseudomonas aeruginosa dominates the assembly of the MinC-MinD copolymers.
(The Journal of biological chemistry, 2018-04-02)Cell division of rod-shaped bacteria requires the Z ring, a ring of FtsZ filaments associated with the inner-membrane wall. The MinCDE proteins help localize the Z ring to the center of the Escherichia coli cell. MinC, which ... -
The phospholipid-repair system LplT/Aas in Gram-negative bacteria protects the bacterial membrane envelope from host phospholipase A2 attack.
(J Biol Chem, 2018-01-18)Secretory phospholipases A2 (sPLA2) are potent components of mammalian innate-immunity antibacterial mechanisms. sPLA2 enzymes attack bacteria by hydrolyzing bacterial membrane phospholipids, causing membrane disorganization ...