Browsing by Subject "bcl-x-l"

Now showing items 1-1 of 1

Mono- or Double-Site Phosphorylation Distinctly Regulates the Proapoptotic Function of Bax

Wang, Qinhong; Sun, Shi-Yong; Khuri, Fadlo; Curran, Walter J; Deng, Xingming (2010)

Bax is the major multidomain proapoptotic molecule that is required for apoptosis. It has been reported that phosphorylation of Bax at serine(S) 163 or S184 activates or inactivates its proapoptotic function, respectively. ...