Browsing by Subject "binding"
Now showing items 1-4 of 4
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Calcium Dependence of Fibrin Nanomechanics: The gamma 1 Calcium Mediates the Unfolding of Fibrinogen Induced by Force Applied to the "A-a" Bond
(2010)The interactions between the constituent monomers of fibrin, the polymerized protein network that provides the structural stability of blood clots, ale frequently under stress because of the dynamic nature of blood flow ... -
Conformational kinetics reveals affinities of protein conformational states.
(Proc Natl Acad Sci U S A, 2015-07-28)Most biological reactions rely on interplay between binding and changes in both macromolecular structure and dynamics. Practical understanding of this interplay requires detection of critical intermediates and determination ... -
Enhanced Biomolecular Binding to Beads on a Digital Microfluidic Device
(2022)Digital microfluidic (DMF) technology is being utilized for commercial applications such as point-of-care diagnostics, sample processing and genomic library preparation. Advances in this field offer exciting possibilities ... -
Kinetics of Coupled Binding and Conformational Change in Proteins and RNA
(2015)Ligand binding can modulate function of proteins and nucleic acids by changing both the populations of functionally distinct conformational states and the timescales on which they interconvert. For this reason, both thermodynamic ...
