Now showing items 1-5 of 5

    • Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption. 

      Siddiqui, Sana; Lustig, Ana; Carter, Arnell; Sankar, Mathavi; Daimon, Caitlin M; Premont, Richard T; Etienne, Harmonie; ... (18 authors) (Aging (Albany NY), 2017-03-04)
      Recent research has proposed that GIT2 (G protein-coupled receptor kinase interacting protein 2) acts as an integrator of the aging process through regulation of 'neurometabolic' integrity. One of the commonly accepted hallmarks ...
    • Heading Down the Wrong Pathway: on the Influence of Correlation within Gene Sets 

      Gatti, Daniel M; Barry, William T; Nobel, Andrew B; Rusyn, Ivan; Wright, Fred A (2010)
      Background: Analysis of microarray experiments often involves testing for the overrepresentation of pre-defined sets of genes among lists of genes deemed individually significant. Most popular gene set testing methods assume ...
    • Hippocampal Transcriptomic and Proteomic Alterations in the BTBR Mouse Model of Autism Spectrum Disorder. 

      Daimon, Caitlin M; Jasien, Joan M; Wood, William H; Zhang, Yongqing; Becker, Kevin G; Silverman, Jill L; Crawley, Jacqueline N; ... (9 authors) (Front Physiol, 2015)
      Autism spectrum disorders (ASD) are complex heterogeneous neurodevelopmental disorders of an unclear etiology, and no cure currently exists. Prior studies have demonstrated that the black and tan, brachyury (BTBR) T+ Itpr3tf/J ...
    • The 2018 Bioinformatics Open Source Conference (GCCBOSC 2018). 

      Harris, Nomi L; Wiencko, Heather; Chapman, Brad; Cock, Peter JA; Hokamp, Karsten; Lapp, Hilmar; Fields, Chris; ... (8 authors) (F1000Research, 2018-01)
      In 2018, the annual Bioinformatics Open Source Conference was held for the first time in conjunction with the Galaxy Community Conference, as an experiment to see if we could reach people in the bioinformatics community ...
    • Using Protein-Likeness to Validate Conformational Alternatives 

      Keedy, Daniel Austin (2012)
      Proteins are among the most complex entities known to science. Composed of just 20 fundamental building blocks arranged in simple linear strings, they nonetheless fold into a dizzying array of architectures that carry out ...