Browsing by Subject "calcium-permeable channels"
Now showing items 1-1 of 1
UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling. (Proc Natl Acad Sci U S A, 2013-08-20)At our body surface, the epidermis absorbs UV radiation. UV overexposure leads to sunburn with tissue injury and pain. To understand how, we focus on TRPV4, a nonselective cation channel highly expressed in epithelial skin ...