Browsing by Subject "cancer genomics"
Now showing items 1-3 of 3
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Graph-based Approaches for Cancer Genomics, with Applications to Cancer Signaling and Dependencies
(2018)The era of widely applicable sequencing and genomic technologies led to the generation of many large-scale datasets exploring genomes, transcriptomes, or epigenomes of tumors. Availability of a wide range of datasets necessitated ... -
Methods for Systematic Exploratory Analysis of Gene Expression Data with Applications to Cancer Genomics
(2017)Advances in technologies for gene expression profiling have resulted in an unprecedented abundance of gene expression data. However, computational methods available for the exploratory analysis of such data are limited in ... -
Narrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypes.
(Genes Cancer, 2016-07)Functional genomics approaches such as gain- and loss-of-function screening can efficiently reveal genes that control cancer cell growth, survival, signal transduction, and drug resistance, but distilling the results of ...
