Now showing items 1-4 of 4

    • Conformational kinetics reveals affinities of protein conformational states. 

      Daniels, Kyle G; Oas, Terrence Gilbert; Suo, Y (Proc Natl Acad Sci U S A, 2015-07-28)
      Most biological reactions rely on interplay between binding and changes in both macromolecular structure and dynamics. Practical understanding of this interplay requires detection of critical intermediates and determination ...
    • Kinetics of Coupled Binding and Conformational Change in Proteins and RNA 

      Daniels, Kyle Gabriel (2015)
      Ligand binding can modulate function of proteins and nucleic acids by changing both the populations of functionally distinct conformational states and the timescales on which they interconvert. For this reason, both thermodynamic ...
    • Making Sense of Health Information Technology 

      Kitzmiller, Rebecca Rutherford (2012)
      <bold>Background:<bold> Hospital adoption of health information technology (HIT) systems is promoted as essential to decreasing medical error and their associated 44,000 annual deaths and $17 billion in healthcare costs ...
    • The psychology of legitimacy: Implications for organizational leadership and change 

      Tost, Leigh Plunkett (2010)
      Three distinct chapters explore the individual-level dynamics of legitimacy judgments and support for leaders and their initiatives. Chapter 1 develops a theoretical framework for understanding the content of legitimacy ...