Browsing by Subject "cisplatin"

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Competing Actions of Type 1 Angiotensin II Receptors Expressed on T Lymphocytes and Kidney Epithelium during Cisplatin-Induced AKI.

Zhang, Jiandong; Rudemiller, Nathan P; Patel, Mehul B; Wei, QingQing; Karlovich, Norah S; Jeffs, Alexander D; Wu, Min; ... (13 authors) (J Am Soc Nephrol, 2016-08)

Inappropriate activation of the renin-angiotensin system (RAS) contributes to many CKDs. However, the role of the RAS in modulating AKI requires elucidation, particularly because stimulating type 1 angiotensin II (AT1) receptors ...
Enhancing Cisplatin Delivery and Anti-tumor Efficacy Using Hyperthermia

Landon, Chelsea Dawn (2013)

Mild hyperthermia (39°C-43°C) has numerous therapeutic benefits as an adjuvant therapy in the treatment of a variety of tumor types. Hyperthermia increases tumor blood flow and vascular permeability, promoting drug delivery ...