Now showing items 1-3 of 3

    • Mechanisms and functional roles of glutamatergic synapse diversity in a cerebellar circuit. 

      Zampini, V; Liu, JK; Diana, MA; Maldonado, PP; Brunel, Nicolas; Dieudonné, S (Elife, 2016-09-19)
      Synaptic currents display a large degree of heterogeneity of their temporal characteristics, but the functional role of such heterogeneities remains unknown. We investigated in rat cerebellar slices synaptic currents in ...
    • New Insights into GPCR–Transducer Coupling 

      Cahill, Thomas J. (2018)
      β-arrestins (βarrs) interact with G protein-coupled receptors (GPCRs) to desensitize G protein signaling, initiate signaling on their own, and mediate receptor endocytosis.  Using a panel of GPCRs believed to couple differently ...
    • β-Adrenergic Receptor Kinase-1 Levels in Catecholamine-Induced Myocardial Hypertrophy 

      Dolber, Paul Christian; Iaccarino, Guido; Koch, Walter J; Lefkowitz, Robert J (1999-01)
      Pressure overload ventricular hypertrophy is accompanied by dysfunctional β-adrenergic receptor signaling due to increased levels of the β-adrenergic receptor kinase-1, which phosphorylates and desensitizes β-adrenergic ...