Browsing by Subject "diabetes"
Now showing items 1-15 of 15
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Broad Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or β-cell Metabolism in the Absence of Dietary Overnutrition
(2018)SIRT3 is an NAD+-dependent mitochondrial protein deacetylase purported to influence cellular and systemic metabolism through modulation of the mitochondrial acetylproteome. Fuel-stimulated insulin secretion from pancreatic ... -
Commentary on Winhusen et al. (2019): Substance use disorders, chronic diseases, and electronic health records-a paradigm for screening and intervention.
(Addiction (Abingdon, England), 2019-08) -
Comunicación y confianza: La influencia cultural en la comunicación entre doctores y pacientes latinos en Durham
(2017-04-30)Los latinos en Durham, Carolina del Norte, constituyen un componente significativo de la comunidad en términos de tamaño y aportación social y económica. Sin embargo, experimentan barreras al acceso y una peor calidad de ... -
Defining Ankyrin-b Syndrome: Characterization of Ankyrin-b Variants in Mice and Men and the Discovery of a Role for Ankyrin-b in Parasympathetic Control of Insulin Release
(2009)Studies in the ankyrin-B+/- mouse reveal that ankyrin-B deficiency is associated with both the benefits of enhanced cardiac contractility and the costs of arrhythmia, early senescence, reduced lifespan, and impaired glucose ... -
Egg Consumption and Risk of Total and Cause-Specific Mortality: An Individual-Based Cohort Study and Pooling Prospective Studies on Behalf of the Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group.
(Journal of the American College of Nutrition, 2019-06-07)The associations of egg consumption with total, coronary heart disease (CHD), and stroke mortality are poorly understood. We prospectively evaluated the link between total, CHD, and stroke mortality with egg consumption ... -
Exploration and Application of Dimensionality Reduction and Clustering Techniques to Diabetes Patient Health Records
(2017-05-24)This research examines various data dimensionality reduction techniques and clustering methods. The goal was to apply these ideas to a test dataset and a healthcare dataset to see how they practically work and what conclusions ... -
Glycemic Control Predicts Severity of Hepatocyte Ballooning and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease.
(Hepatology (Baltimore, Md.), 2021-03-16)<h4>Background and aims</h4>Whether glycemic control, as opposed to diabetes status, is associated with the severity of nonalcoholic fatty liver disease (NAFLD) is unknown. We aimed to evaluate whether degree of glycemic ... -
Impact of diabetes in patients with pulmonary hypertension.
(Pulm Circ, 2015-03)Diabetes complicates management in a number of disease states and adversely impacts survival; how diabetes affects patients with pulmonary hypertension (PH) has not been well characterized. With insulin resistance having ... -
Impact of diabetes in patients with pulmonary hypertension.
(Pulmonary circulation, 2015-03)Diabetes complicates management in a number of disease states and adversely impacts survival; how diabetes affects patients with pulmonary hypertension (PH) has not been well characterized. With insulin resistance having ... -
Metabolic Pathways of Type 2 Diabetes: Intersection of Genetics, Transcriptomics, and Metabolite Profiling
(2008-07-25)Type 2 diabetes is characterized by insufficient insulin secretion to maintain euglycemia in the setting of peripheral insulin resistance. The majority of insulin-resistant diabetics are obese, yet not all insulin-resistant ... -
Prescriber continuity and medication availability in older adults with cardiometabolic conditions.
(SAGE Open Med, 2018)Background: Many older adults have multiple conditions and see multiple providers, which may impact their use of essential medications. Objective: We examined whether the number of prescribers of these medications was associated ... -
Sequential Multiple Assignment Randomized Trial (SMART) to identify optimal sequences of telemedicine interventions for improving initiation of insulin therapy: A simulation study.
(BMC medical research methodology, 2021-09-30)<h4>Background</h4>To examine the value of a Sequential Multiple Assignment Randomized Trial (SMART) design compared to a conventional randomized control trial (RCT) for telemedicine strategies to support titration of insulin ... -
Shared Metabolic Pathways in Fuel-Stimulated Insulin Secretion
(2009)Insulin secretion is a fundamental process of pancreatic beta-cells required for the maintenance of glucose homeostasis. Fuel-stimulated insulin secretion occurs in proportion to the rate of metabolism of fuel substrates, ... -
Special Considerations in the Management of Diabetes in Women.
(Journal of women's health (2002), 2018-05-10)Type 2 diabetes and prediabetes are heterogeneous diseases that directly affect over 115 million Americans. Considerable gender differences exist with regard to diabetes risk factors, hormonal effects on glucose, ... -
Understanding Patients’ Needs and Healthcare Seeking Behavior in Rural Southern India: The Comparison of Providers through Patients’ Perceptions and Cost Issues
(2016)This study explores patients’ needs in rural Thanjavur, southern India through understanding how people with diabetes choose providers and perceive care-seeking experience. To measure perception, the study surveyed people ...
