Browsing by Subject "endothelial cells"
Now showing items 1-5 of 5
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Angiopoietin-1 is required for Schlemm's canal development in mice and humans.
(The Journal of clinical investigation, 2017-12)Primary congenital glaucoma (PCG) is a leading cause of blindness in children worldwide and is caused by developmental defects in 2 aqueous humor outflow structures, Schlemm's canal (SC) and the trabecular meshwork. We previously ... -
Characterizing the Role of the Previously Undescribed Protein Caskin2 in Vascular Biology
(2016)Maintenance of vascular homeostasis is an active process that is dependent on continuous signaling by the quiescent endothelial cells (ECs) that line mature vessels. Defects in vascular homeostasis contribute to numerous ... -
Elevated PTH induces endothelial to chondrogenic transition in aortic endothelial cells.
(Am J Physiol Renal Physiol, 2016-08-31)Previous studies have shown that increased parathyroid hormone (PTH) due to secondary hyperparathyroidism in chronic kidney disease accelerates the arteriosclerotic fibrosis and calcification. Although the underlying mechanisms ... -
Inhalation of an RNA aptamer that selectively binds extracellular histones protects from acute lung injury.
(Molecular therapy. Nucleic acids, 2023-03)Acute lung injury (ALI) is a syndrome of acute inflammation, barrier disruption, and hypoxemic respiratory failure associated with high morbidity and mortality. Diverse conditions lead to ALI, including inhalation of toxic ... -
Umbilical Cord Blood Derived Endothelial Progenitor Cells: Isolation, Characterization, and Adhesion Potential in Vitro and in Vivo
(2009)The number one cause of death in the industrialized world, atherosclerosis, can be treated through a variety of methods: angioplasty, stenting, vein graft bypass, synthetic grafts, and maybe one day tissue engineering vessels ...
