Browsing by Subject "fMRI"
Now showing items 1-20 of 40
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A Connectome Wide Functional Signature of Transdiagnostic Risk for Mental Illness
(Biological Psychiatry, 2018-04-10)Background High rates of comorbidity, shared risk, and overlapping therapeutic mechanisms have led psychopathology research towards transdiagnostic dimensional investigations of clustered symptoms. One influential framework ... -
A Novel Experimental Method for Measuring Proactive and Reactive Responses to Threat and an Examination of Their Personality and Neural Correlates
(2015)The goal of this dissertation is to characterize goal directed proactive behavioral responses to threat as well as reactive responses to threat exposure, and to identify the neural and personality correlates of individual ... -
Age mediation of frontoparietal activation during visual feature search.
(Neuroimage, 2014-11-15)Activation of frontal and parietal brain regions is associated with attentional control during visual search. We used fMRI to characterize age-related differences in frontoparietal activation in a highly efficient feature ... -
Assessment of the Spatial and Temporal Distribution of Functional Connectivity in Resting-State BOLD fMRI
(2016)Recent research into resting-state functional magnetic resonance imaging (fMRI) has shown that the brain is very active during rest. This thesis work utilizes blood oxygenation level dependent (BOLD) signals to investigate ... -
Chasing Dreams or Avoiding Ruin: Neural Activation to Goal Priming in Low-Income vs. Control Adolescents
(2021-04-09)Goals are central to our identities. An important process related to goals is self-regulation: the process of pursuing goals despite internal and external forces that might disrupt it. Adolescents have been shown to struggle ... -
Cognitive Neurostimulation: Learning to Volitionally Invigorate Mesolimbic Reward Network Activation
(2015)The brain’s dopaminergic system is critical to adaptive behaviors, and is centrally implicated in various pathologies. For decades, research has aimed at better characterizing what drives the mesolimbic dopamine system and ... -
Contributions Of the Human Medial Prefrontal Cortex To Associative Recognition Memory: Evidence From Functional Neuroimaging
(2016)Neuroimaging studies of episodic memory, or memory of events from our personal past, have predominantly focused their attention on medial temporal lobe (MTL). There is growing acknowledgement however, from the cognitive ... -
Cumulative stress in childhood is associated with blunted reward-related brain activity in adulthood.
(Soc Cogn Affect Neurosci, 2016-03)Early life stress (ELS) is strongly associated with negative outcomes in adulthood, including reduced motivation and increased negative mood. The mechanisms mediating these relations, however, are poorly understood. We examined ... -
Dissociable Influence of Reward and Punishment Motivation on Declarative Memory Encoding and its Underlying Neurophysiology
(2012)Memories are not veridical representations of the environment. Rather, an individual's goals can influence how the surrounding environment is represented in long-term memory. The present dissertation aims to delineate the ... -
Dopaminergic mechanisms of individual differences in the discounting and subjective value of rewards
(2022)Everyday, animals make decisions that require balancing tradeoffs like time delays, uncertainty, and physical effort demands with the prospect of rewards like food or money. The tendency to devalue rewards according to ... -
Effect of Repetitive Transcranial Magnetic Stimulation on the Structural and Functional Connectome in Patients with Major Depressive Disorder
(2017-05-08)Through this whole-brain exploratory analysis, our aim is to study the effect of repetitive transcranial magnetic stimulation (rTMS) on the structural and functional connectivity of patients with major depressive disorder. ... -
Effects of HIV infection and cocaine dependence on brain activity during risky and ambiguous decision making
(2017-06-17)HIV infection can be characterized as a brain disease with 47 percent of infected patients experiencing neurocognitive disorders. MRI studies of HIV patients reveal alterations in gray and white matter. Individuals addicted ... -
Encoding-Retrieval Relationships in Episodic Memory: A Functional Neuroimaging Perspective
(2015)The ability to re-experience the past is a defining feature of episodic memory. Yet we know that even the most detailed memories are distinct from the initial experiences to which they refer. This relationship between the ... -
Frontoparietal activation during visual conjunction search: Effects of bottom-up guidance and adult age.
(Hum Brain Mapp, 2017-04)We conducted functional magnetic resonance imaging (fMRI) with a visual search paradigm to test the hypothesis that aging is associated with increased frontoparietal involvement in both target detection and bottom-up attentional ... -
Functional Brain Networks Underlying Anticipation in Motivated Behavior
(2018)Anticipation is a state of expectancy for something that will happen, and it allows us to use past learning to prepare for and make predictions about the future. Studies have shown that anticipation influences behavioral ... -
Functional Neuroimaging Investigations of Human Memory: Comparisons of Successful Encoding and Retrieval for Relational and Item Information
(2007-05-10)Memory is a complex and multifaceted entity. Cognitive psychology has adopted terminology to help simplify the study of memory. For example, one can consider the cognitive process the brain is engaged in, such as encoding ... -
Individual differences in regulatory focus predict neural response to reward.
(Soc Neurosci, 2016-04-30)Although goal pursuit is related to both functioning of the brain's reward circuits and psychological factors, the literatures surrounding these concepts have often been separate. Here, we use the psychological construct ... -
Integrated Parallel Reception, Excitation, and Shimming (iPRES) Head Coils: Application to Functional MRI and Development of a Battery Powered System
(2018)In MRI, magnetic susceptibility differences at air/tissue interfaces result in main magnetic field (B0) inhomogeneities, which in turn cause artifacts such as distortions and signal loss, especially in gradient-echo echo-planar ... -
Interoceptive Contributions to Motivational and Affective Modulators of Memory Formation
(2015)Biological drives such as hunger, thirst, and sexual reproduction are potent motivators of behavior. Extrinsic rewards in the environment (i.e. food, drink, money) are also important behavioral and cognitive motivators. ... -
Introduction of novel video-based tasks to clinical fMRI: Comparing traditional fMRI tasks with novel video-based tasks for mapping brain language areas
(2016-06-07)Recently, blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) has become a routine clinical procedure for localization of language and motor brain regions and has been replacing more invasive ...
