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Browsing by Subject "fibrosis"
Now showing items 1-5 of 5
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Cellular and Molecular Mediators of Bronchiolitis Obliterans-like Pathological Changes in a Murine Model of Chlorine Gas Inhalation
(2013)Bronchiolitis Obliterans (BO) is a major cause of chronic airway dysfunction after toxic chemical inhalation. The pathophysiology of BO is not well understood, but epithelial cell injury has been closely associated with ... -
Characterization of the Foreign Body Response to Common Surgical Biomaterials in a Murine Model.
(European journal of plastic surgery, 2017-11)BACKGROUND:Implanted biomaterials are subject to a significant reaction from the host, known as the foreign body response (FBR). We quantified the FBR to five materials following subcutaneous implantation in mice. MATERIALS ... -
Does hand stiffness reflect internal organ fibrosis in diabetes mellitus?
(Frontiers in clinical diabetes and healthcare, 2023-01)Fibrosis leads to irreversible stiffening of tissue and loss of function, and is a common pathway leading to morbidity and mortality in chronic disease. Diabetes mellitus (both type 1 and type 2 diabetes) are associated ... -
Experimental inhibition of porcupine-mediated Wnt O-acylation attenuates kidney fibrosis.
(Kidney Int, 2016-05)Activated Wnt signaling is critical in the pathogenesis of renal fibrosis, a final common pathway for most forms of chronic kidney disease. Therapeutic intervention by inhibition of individual Wnts or downstream Wnt/β-catenin ... -
The clinical utility of FibroScan(®) as a noninvasive diagnostic test for liver disease.
(Med Devices (Auckl), 2014)An important aspect of managing chronic liver disease is assessing for evidence of fibrosis. Historically, this has been accomplished using liver biopsy, which is an invasive procedure associated with risk for complications ...
