Browsing by Subject "genome"
Now showing items 1-12 of 12
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1997 Delegates to the Second International Strategy Meeting on Human Genome Sequencing in Bermuda from Gert-Jan van Ommen
(2016-08-31)Photographs from the February 1997 Bermuda meeting. Courtesy of Gert-Jan van Ommen. -
2000 NHGRI e-mail request for HGP sequencing center information, and corresponding aggregate data from NHGRI, compiled by Kris Wetterstrand
(2016-08-31)Email exchange in 2013 between Kathryn Maxson (Duke) and Kris Wetterstrand (NHGRI), regarding country funding and other data for the HGP sequencing centers. Also includes the email request for such information, from NHGRI ... -
2011 18 August Mark Guyer-Jane Peterson interview
(2011-08-18)Mark Guyer and Jane Peterson, in-person interview with Kathryn Maxson and Robert Cook-Deegan, conducted in Rockville, MD (NIH campus), 18 August 2011. Mark Guyer and Jane Peterson were grants program officers at the NIH ... -
2012 09 February Jean Weissenbach interview
(2016-08-31)Jean Weissenbach, telephone interview by Kathryn Maxson and Robert Cook-Deegan, conducted from Durham, NC 09 February 2012. Jean Weissenbach, a leader in French genetic mapping, directed the French national sequencing center, ... -
Characterizing Genetic Drivers of Lymphoma through High-Throughput Sequencing
(2016)The advent of next-generation sequencing, now nearing a decade in age, has enabled, among other capabilities, measurement of genome-wide sequence features at unprecedented scale and resolution. In this dissertation, I describe ... -
Cyclic Sulfones as Novel P3-Caps for Hepatitis C Virus NS3/4A (HCV NS3/4A) Protease Inhibitors: Synthesis and Evaluation of Inhibitors with Improved Potency and Pharmacokinetic Profiles
(2010)HCV infection affects more than 170 million people worldwide and many of those patients will reach the end stage complications of the disease which include hepatocarcinoma and liver failure. The success rate for treatment ... -
Detection of Alternative Splice Variants at the Proteome Level in Aspergillus flavus
(2010)Identification of proteins from proteolytic peptides or intact proteins plays an essential role in proteomics. Researchers use search engines to match the acquired peptide sequences to the target proteins. However, search ... -
Genomic Insights Into the Lichen Symbiosis: <italic>Cladonia grayi</italic> as a Model Lichen
(2011)Lichens are symbioses between a fungus and a photosynthesizing partner such as a green alga or a cyanobacterium. Unlike mycorrhizal or rhizobial symbioses, the lichen symbiosis is not well understood either morphologically ... -
Potential Influence of Staphylococcus aureus Clonal Complex 30 Genotype and Transcriptome on Hematogenous Infections.
(Open Forum Infect Dis, 2015-09)Background. The contemporary Staphylococcus aureus clonal complex (CC) 30 lineage is associated with complicated infections, including endocarditis and osteomyelitis. This lineage diverged from the phage-type 80/81 S aureus ... -
The Glucocorticoid-Mediated Dynamics of Genome Architecture
(2018)Human cells are perpetually receiving and responding to a variety of intrinsic and extrinsic signals. A primary mechanism by which cells carry out these responses is via changes in the regulation of gene expression. Many ...
