Browsing by Subject "genome stability"
Now showing items 1-4 of 4
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Chromatin Dynamics and Regulation of the Helicase During Replication Initiation
(2021)DNA replication is an intricate process within eukaryotic cells that must be precisely executed to preserve genetic information. This process begins at multiple start sites, or origins of replication, along each chromosome ... -
Defining the Role of the Histone Methyltransferase, PR-Set7, in Maintaining the Genome Integrity of Drosophila Melanogaster
(2016)The complete and faithful duplication of the genome is essential to ensure normal cell division and organismal development. Eukaryotic DNA replication is initiated at multiple sites termed origins of replication that are ... -
Genetic Control of Genomic Alterations Induced in Yeast by Interstitial Telomeric Sequences
(2018)Telomeric sequences are often located internally on the chromosome in addition to their usual positions at the ends of the chromosome. These internally-located telomeric sequences have been termed “interstitial telomeric ... -
Molecular Characterization of Mitotic Homologous Recombination Outcomes in Saccharomyces cerevisiae
(2017)Mitotic homologous recombination (HR) is vital for accurate repair of DNA strand breaks caused by endogenous and exogenous sources. However, this high-fidelity repair pathway also can lead to genome rearrangements when dispersed ...
