Browsing by Subject "hyperthermia"
Now showing items 1-4 of 4
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Assembly of Highly Asymmetric Genetically-Encoded Amphiphiles for Thermally Targeted Delivery of Therapeutics
(2013)Traditional small molecule chemotherapeutics show limited effectiveness in the clinic as their poor pharmacokinetics lead to rapid clearance from circulation and their exposure to off-target tissues results in dose-limiting ... -
Drug Delivery and Anti-Vascular Effects of Temperature Sensitive Liposomal Doxorubicin
(2010)Traditionally, the goal of nanoparticle-based chemotherapy has been to decrease normal tissue toxicity by improving drug specificity to tumor. Relying on the EPR effect (Enhanced Permeability and Retention), a host ... -
Enhancing Cisplatin Delivery and Anti-tumor Efficacy Using Hyperthermia
(2013)Mild hyperthermia (39°C-43°C) has numerous therapeutic benefits as an adjuvant therapy in the treatment of a variety of tumor types. Hyperthermia increases tumor blood flow and vascular permeability, promoting drug delivery ... -
Ultrasound Catheter Transducers for Intracranial Brain Imaging and Therapy
(2011)Each year, over 13,000 people in the United States die from a primary malignant brain tumor. Currently, primary BTs are treated most commonly by surgery, radiotherapy, and systemic chemotherapy, though each of these methods ...
