Browsing by Subject "iPSC"
Now showing items 1-3 of 3
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Developing iPSC-derived neuronal cell lines for studying the effect of synuclein overexpression in the context of synucleinopathies
(2016-04-25)Synucleinopathies are a group of neurodegenerative disorders that share a common pathological lesion composed of intracellular aggregates of α-synuclein (α-syn). This study focuses on two diseases in this group: Parkinson’s ... -
Development of a High-Throughput Human iPSC Chondrogenesis Platform and Applications for Arthritis Disease Modeling
(2019)The differentiation of human induced pluripotent stem cells (hiPSCs) to prescribed cell fates enables the engineering of patient-specific tissue types, such as hyaline cartilage, for applications in regenerative medicine, ... -
Osteochondral Tissue Engineering with Induced Pluripotent Stem Cells
(2018)With growing numbers of increasingly younger patients suffering debilitating arthropathies, the need for simple models that recapitulate the complex interplay between distinct joint tissues, and grafts that emulate these ...
