Browsing by Subject "inflammation mediators"

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Mast cell activation and arterial hypotension during proximal aortic repair requiring hypothermic circulatory arrest.

Kertai, Miklos D; Cheruku, Sreekanth; Qi, Wenjing; Li, Yi-Ju; Hughes, G Chad; Mathew, Joseph P; Karhausen, Jörn A (J Thorac Cardiovasc Surg, 2017-01)

OBJECTIVE: Aortic surgeries requiring hypothermic circulatory arrest evoke systemic inflammatory responses that often manifest as vasoplegia and hypotension. Because mast cells can rapidly release vasoactive and proinflammatory ...