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Browsing by Subject "kinetics"
Now showing items 1-9 of 9
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Adsorption of a Nonionic Symmetric Triblock Copolymer on Surfaces with Different Hydrophobicity
(2010)This study investigates the adsorption of a symmetric triblock nonionic polymer comprising ethylene oxide (EO) and propylene oxide (PO) blocks (Pluronic P-105, EO37PO56EO37) on a range of substrates including hydrophobic, ... -
Distributions of Parameters and Features of Multiple Bond Ruptures in Force Spectroscopy by Atomic Force Microscopy
(2010)Force spectroscopy measurement of rupture forces of bound molecules becomes an important physicochemical tool in characterizing intermolecular interactions, Atomic force microscopy (AFM) measurements are among the most common ... -
Kinetic Characterization of the Coupled Folding and Binding Mechanism of Bacterial RNase P Protein: an Intrinsically Unstructured Protein
(2009)Understanding the interconversion between the thermodynamically distinguishable states present in a protein folding pathway provides not only the kinetics and energetics of protein folding but also insights into the functional ... -
Kinetics of Coupled Binding and Conformational Change in Proteins and RNA
(2015)Ligand binding can modulate function of proteins and nucleic acids by changing both the populations of functionally distinct conformational states and the timescales on which they interconvert. For this reason, both thermodynamic ... -
M6A Reshapes the Folding and Recognition Landscape of RNAs
(2021)Ribonucleic acid (RNA) is a versatile and dynamic biomolecule that serves as an indispensable component in the central dogma of molecular biology. The realization that RNA plays a wide variety of roles in gene expression ... -
Mechanical Distortion of Protein Receptor Decreases the Lifetime of a Receptor-Ligand Bond
(2010)Substantial experimental evidence indicates that the mechanical force applied to pull apart non-covalent molecular bonds (such as receptor ligand pairs) can significantly decrease the bond lifetime. This evidence is often ... -
Model Studies of Proposed Intermediates in Homogeneous Gold(I) Catalysis
(2012)The ability of gold(I) complexes to function as catalysts for myriad organic transformations has led to a dramatic increase in their utilization. Among the homogeneous reactions catalyzed by gold(I), carbon-carbon ... -
Modeling nitrogen fate in supercritical water oxidation
(2020)Supercritical water oxidation (SCWO) had been investigated as an advanced technology for the removal of inert and stable organics found in wide range of wastes. Ammonia and nitrous oxide are confirmed in outlet of SCWO system ... -
Spontaneous Unfolding-Refolding of Fibronectin Type III Domains Assayed by Thiol Exchange: THERMODYNAMIC STABILITY CORRELATES WITH RATES OF UNFOLDING RATHER THAN FOLDING.
(J Biol Chem, 2017-01-20)Globular proteins are not permanently folded but spontaneously unfold and refold on time scales that can span orders of magnitude for different proteins. A longstanding debate in the protein-folding field is whether unfolding ...
