Browsing by Subject "lactic acidosis"

Now showing items 1-4 of 4

    • Cellular Responses to Lactic Acidosis in Human Cancers 

      Chen, Julia Ling-Yu (2010)
      The physiology of the tumor microenvironment is characterized by lower oxygen (hypoxia), higher lactate, extracellular acidosis and glucose starvation. We examined the global, transcriptional cellular responses to each of ...

    • Genetic Determinants of Cancer Cell Survival in Tumor Microenvironment Stresses 

      Keenan, Melissa Marie (2015)
      In order to propagate a solid tumor, cancer cells must adapt to and survive under various tumor microenvironment (TME) stresses, such as hypoxia or lactic acidosis. Additionally, cancer cells exposed to these stresses are ...

    • Machine Learning Consensus Clustering Approach for Patients with Lactic Acidosis in Intensive Care Units. 

      Pattharanitima, Pattharawin; Thongprayoon, Charat; Petnak, Tananchai; Srivali, Narat; Gembillo, Guido; Kaewput, Wisit; Chesdachai, Supavit; ... (14 authors) (Journal of personalized medicine, 2021-11)
      Lactic acidosis is a heterogeneous condition with multiple underlying causes and associated outcomes. The use of multi-dimensional patient data to subtype lactic acidosis can personalize patient care. Machine learning consensus ...

    • Machine Learning Prediction Models for Mortality in Intensive Care Unit Patients with Lactic Acidosis. 

      Pattharanitima, Pattharawin; Thongprayoon, Charat; Kaewput, Wisit; Qureshi, Fawad; Qureshi, Fahad; Petnak, Tananchai; Srivali, Narat; ... (16 authors) (Journal of clinical medicine, 2021-10)
      Lactic acidosis is the most common cause of anion gap metabolic acidosis in the intensive care unit (ICU), associated with poor outcomes including mortality. We sought to compare machine learning (ML) approaches versus logistic ...