Browsing by Subject "lung cancer"
Now showing items 1-7 of 7
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A Model of Lung Tumor Angiogenesis in a Biomimetic Poly(ethylene glycol)-based Hydrogel System
(2016)Tumor angiogenesis is critical to tumor growth and metastasis, yet much is unknown about the role vascular cells play in the tumor microenvironment. A major outstanding challenge associated with studying tumor angiogenesis ... -
Application of Phylogenetic Analysis in Cancer Evolution
(2018)Cancer is a major threat to human health and results in 1 in 6 deaths globally. Despite an extraordinary amount of effort and money spent, eradication or control of advanced disease has not yet been achieved. Understanding ... -
Genetic variants in DDO and PEX5L in peroxisome-related pathways predict non-small cell lung cancer survival.
(Molecular carcinogenesis, 2022-05-03)Peroxisomes play a role in lipid metabolism and regulation of reactive oxygen species, but its role in development and progression of non-small cell lung cancer (NSCLC) is not well understood. Here, we investigated ... -
"I already know that smoking ain't good for me": Patient and Clinician Perspectives on Lung Cancer Screening Decision-Making Discussions as a Teachable Moment.
(Chest, 2020-04-15)BACKGROUND:Lung cancer screening (LCS) is now recommended for people at high risk of dying of lung cancer. RESEARCH QUESTION:The purpose of this study was to use the LCS decision discussion as a case study to understand ... -
Impact of Esophageal Motion on Dosimetry and Toxicity With Thoracic Radiation Therapy.
(Technology in cancer research & treatment, 2019-01)PURPOSE:To investigate the impact of intra- and inter-fractional esophageal motion on dosimetry and observed toxicity in a phase I dose escalation study of accelerated radiotherapy with concurrent chemotherapy for locally ... -
Radiogenomics for Radiation Treatment Assessment of Advanced Lung Cancers
(2019)Background: Radiomics describes the study of converting medical images into high-dimensional quantitative features and following analysis for further decision making and genomics focuses on the understanding genomes of individual ... -
Role of Type III TGF-β Receptor Shedding in Regulating Tumorigenesis
(2019)The type III TGF-β receptor (TβRIII) is a TGF-β co-receptor that presents ligand to the type II TGF-β receptor to initiate signaling. TβRIII also undergoes ectodomain shedding to release a soluble form (sTβRIII) that can ...
