Browsing by Subject "malaria"
Now showing items 1-19 of 19
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An evolutionary genomics approach towards understanding Plasmodium vivax in central Africa
(2022)Increased attention has recently been placed on understanding the natural variation of the malaria parasite Plasmodium vivax across the globe, as in 2020 alone, P. vivax caused an estimated 4.5 million malaria cases and ... -
A Risk‐Risk Trade‐off: Insecticide Use for Malaria Control
(2011-04-29)Malaria is among the top causes of death in low-income countries. Because it is transmitted through a mosquito vector, programs to reduce or control these insects receive much attention. Recently, concerns have increased ... -
Community Knowledge and Acceptance of Larviciding for Malaria Control in a Rural District of East-Central Tanzania
(Int. J. Environ. Res. Public Health, 2014)The use of microbial larvicides, a form of larval source management, is a less commonly used malaria control intervention that nonetheless has significant potential as a component of an integrated vector management strategy. ... -
Comparing actual and perceived causes of fever among community members in a low malaria transmission setting in northern Tanzania.
(Trop Med Int Health, 2013-11)OBJECTIVE: To compare actual and perceived causes of fever in northern Tanzania. METHODS: In a standardised survey, heads of households in 30 wards in Moshi, Tanzania, were asked to identify the most common cause of fever ... -
Elucidating Plasmodium Liver Stage Biology Through Transcriptomic Approaches
(2018)Malaria is one of the leading causes of mortality attributed to infectious diseases worldwide. Every year, hundreds of thousands of children succumb to the disease and hundreds of millions more suffer the characteristic ... -
Exploring Kinases of Metabolism and Signaling in the Malaria Parasite Plasmodium
(2018)Plasmodium is the causal agent of malaria, which is a parasitic disease that affects more than 215 million people annually and is endemic in 91 countries worldwide. Unfortunately, the parasites have developed resistance ... -
Human Genetic Variation in VAC14 Regulates Pathogen Entry and Risk of Infectious Disease
(2017)Human genetic variation can be leveraged to understand the subtleties of how common variants with small effect sizes can alter cellular phenotypes and ultimately affect susceptibility to pathogenic disease. By combining ... -
Improving the Modeling of Government Surveillance Data: a Case Study on Malaria in the Brazilian Amazon
(2013)The study of the effect of the environment (e.g., climate and land use) on disease typically relies on aggregate disease data collected by the government surveillance network. The usual approach to analyze these data, however, ... -
Indian Toilets and Tanzanian Mosquito Nets: Understanding Households' Environmental Health Decisions in Developing Countries
(2008-04-25)Diarrhea and malaria are two of the most devastating public health threats in the developing world, resulting in millions of childhood deaths each year. Part of the challenge in addressing these threats arises from the ... -
Invasive Salmonella infections in areas of high and low malaria transmission intensity in Tanzania.
(Clin Infect Dis, 2014-03)BACKGROUND: The epidemiology of Salmonella Typhi and invasive nontyphoidal Salmonella (NTS) differs, and prevalence of these pathogens among children in sub-Saharan Africa may vary in relation to malaria transmission intensity. ... -
Investigation of Specialized Metabolites in Apicomplexan Parasite Life Cycles
(2021)Across the tree of life, specialized metabolites mediate ecological interactions and can ultimately drive evolution. Characterization of these small molecules have led scientists to a greater comprehension of ecological ... -
Malaria Transmission in Border Regions of the Western Amazon: Incorporating watersheds into timeseries analysis to address disease reintroduction and spillover along the Ecuador-Peru border
(2021-04-30)Since 2010, Amazon-basin countries have experienced a 600% increase in malaria cases, the most rapid increase compared to any other region of the world. Border regions have been implicated as important hot spots of malaria ... -
Molecular Interactions between Apicomplexan Parasites and their Host Cells
(2021)Parasitic diseases caused by pathogens of the Apicomplexan phylum result in hundreds of thousands of deaths per year, in addition to being an immense socioeconomic burden on vulnerable populations. A notorious case is that ... -
Mother's Early Age of Marriage Predicts Children Malaria Risk in the Peruvian Amazon
(2013)Objectives:The objective of this study is to determine the malaria risk among children and adolescents from early married families in the Peruvian Amazon. We will explore the hypotheses that younger maternal age of marriage, ... -
Plasmodium falciparum Chaperones and Stress Response
(2020)Malaria remains a major public health challenge that causes 219 million cases and 435,000 deaths in 2017. During their complex life cycle, Plasmodium parasites (the causative agents of malaria) encounter different cellular ... -
Possibilities for the Re-collection and Recycling of Long-Lasting Insecticide-Treated Nets (LLINs) in Sub-Saharan Africa
(2009-04-24)The United States Agency of International Development (USAID) and the World Health Organization (WHO) have relied heavily on the distribution of bednets to curb malaria in sub-Saharan Africa. Additionally, WHO has recently ... -
Probing Pathogen and Host Proteins in Plasmodium Infection
(2018-04-23)Malaria is responsible for hundreds of thousands of deaths annually and is a challenge to treat due to growing resistance to medications by the disease-causing parasite, Plasmodium. Therefore, it is necessary to expand the ... -
The Relationship Between Invasive Nontyphoidal Salmonella Disease, Other Bacterial Bloodstream Infections, and Malaria in Sub-Saharan Africa.
(Clin Infect Dis, 2016-03-15)BACKGROUND: Country-specific studies in Africa have indicated that Plasmodium falciparum is associated with invasive nontyphoidal Salmonella (iNTS) disease. We conducted a multicenter study in 13 sites in Burkina Faso, Ethiopia, ... -
Using GIS and Remote Sensing Technologies to Identify Environmental Variables of Malaria Vector Breeding Sites in Western Kenya
(2016)This study used Landsat 8 satellite imagery to identify environmental variables of households with malaria vector breeding sites in a malaria endemic rural district in Western Kenya. Understanding the influence of environmental ...
