Browsing by Subject "mechanism"
Now showing items 1-7 of 7
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Blood flow controls coagulation onset via the positive feedback of factor VII activation by factor Xa
(2010)Background: Blood coagulation is a complex network of biochemical reactions, which is peculiar in that it is time- and space-dependent, and has to function in the presence of rapid flow. Recent experimental reports suggest ... -
Mechanistic Analysis of Gold(I) Catalysis through Generation and Direct Observation of Reactive Intermediate Analogues
(2019)Cationic gold carbene complexes have attracted significant attention, being postulated as intermediates in a range of gold-catalyzed transformations. Regardless of the remarkable progress in the gold (I) catalysis, ... -
Model Studies of Proposed Intermediates in Homogeneous Gold(I) Catalysis
(2012)The ability of gold(I) complexes to function as catalysts for myriad organic transformations has led to a dramatic increase in their utilization. Among the homogeneous reactions catalyzed by gold(I), carbon-carbon ... -
Molecular Mechanism of Zipper Interacting Protein Kinase
(2011)Diseases caused by smooth muscle dysfunction such as hypertension and asthma are major public health concerns, a better understanding of the signaling pathways that regulate smooth muscle contraction could identify new drug ... -
Nitrogenase Electron Tunneling Pathways Analysis: From the 4Fe-4S Cluster to the P-cluster
(2018)The biological reduction of N2 to NH3 catalyzed by molybdenum nitrogenase requires eight steps to finish a completed catalysis cycle. This reaction cycle is associated with ATP-driven electron transfer (ET) from the Fe protein ... -
Potential consequences of adverse lifestyle factors on decision-making as modeled by the Drosophila melanogaster egg-laying process
(2023-04-14)Studies have shown that lifestyle factors including impaired gut microbiome health, advanced maternal age, and a diet high in sugar may negatively impact cognitive functioning, but their effects on decision-making have not ... -
Resolving teleology’s false dilemma
(Biological Journal of the Linnean Society, 2022)<jats:title>Abstract</jats:title> <jats:p>This paper argues that the account of teleology previously proposed by the authors is consistent with the physical determinism that is implicit across many of the ...
