Browsing by Subject "microglia"
Now showing items 1-6 of 6
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Developmental Programming of Brain and Behavior: A Role for the Innate Immune System of the Placenta and Brain?
(2015)The field of "perinatal programming" has increasingly implicated an adverse early-life environment in the etiology of many chronic health problems and mental disorders. The following dissertation research is based on the ... -
Immunity and Arginine Deprivation in Alzheimer's Disease
(2015)The pathogenesis of Alzheimer’s disease (AD) is a critical unsolved question, and while recent studies have demonstrated a strong association between altered brain immune responses and disease progression, the mechanistic ... -
Neuroimmune Signaling in the Hippocampus: Mechanisms of Risk and Resilience
(2014)The interactions between the brain and the immune system are extensive and each has a profound influence on the other. The hippocampus is a brain region that is strongly impacted by the immune system, especially considering ... -
Reprint of: Preclinical characterization of DUOC-01, a cell therapy product derived from banked umbilical cord blood for use as an adjuvant to umbilical cord blood transplantation for treatment of inherited metabolic diseases.
(Cytotherapy, 2015-09)<h4>Background aims</h4>Cord blood (CB) transplantation slows neurodegeneration during certain inherited metabolic diseases. However, the number of donor cells in the brain of patients does not appear to be sufficient to ... -
Sensory Experience as a Regulator of Structural Plasticity in the Developing Whisker-to-Barrel System.
(Frontiers in cellular neuroscience, 2021-01)Cellular structures provide the physical foundation for the functionality of the nervous system, and their developmental trajectory can be influenced by the characteristics of the external environment that an organism interacts ... -
Tissue-Resident Macrophages in Fungal Infections.
(Frontiers in immunology, 2017-01)Invasive fungal infections result in high morbidity and mortality. Host organs targeted by fungal pathogens vary depending on the route of infection and fungal species encountered. Cryptococcus neoformans infects the respiratory ...
