Browsing by Subject "nuclear magnetic resonance"
Now showing items 1-5 of 5
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Development of new approaches to NMR data collection for protein structure determination
(2007-05-10)Multidimensional nuclear magnetic resonance (NMR) spectroscopy has become one of the most important techniques available for studying the structure and function of biological macromolecules at atomic resolution. The conventional ... -
Kinetic Characterization of the Coupled Folding and Binding Mechanism of Bacterial RNase P Protein: an Intrinsically Unstructured Protein
(2009)Understanding the interconversion between the thermodynamically distinguishable states present in a protein folding pathway provides not only the kinetics and energetics of protein folding but also insights into the functional ... -
Making Nuclear Magnetic Hyperpolarization Practical through Storage in Disconnected Eigenstates
(2015)There are two fundamental limitations in magnetic resonance: the poor signal amplitude and the short duration before the system return to equilibrium. Hyperpolarization methods solve the problem of signal amplitude, however, ... -
Measurements of Conformational Penalties in Nucleic Acids
(2021)Biomolecules are dynamic entities that adopt a variety of conformations in solution. Conformational changes in biomolecules routinely take place when they take part in biochemical processes such as binding and catalysis. ... -
The Search for New/Unknown Signals
(2011)This dissertation focuses on a very special topic in the field of Nuclear Magnetic Resonance (NMR) in solution: Intermolecular Multiple Quantum Coherences, or iMQCs, which can only be created by intermolecular dipolar couplings. ...
