Browsing by Subject "nucleus pulposus"
Now showing items 1-5 of 5
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Cadherin-Mediated Cell-Cell Interactions Regulates Phenotype And Morphology of Nucleus Pulposus Cells Of The Intervertebral Disc
(2015)Juvenile nucleus pulposus (NP) cells of the intervertebral disc (IVD) are large, vacuolated cells that form cell clusters with numerous cell-cell interactions. With maturation and aging, NP cells lose their ability to form ... -
Direct Differentiation of Mouse Induced Pluripotent Stem Cells into Nucleus Pulposus-Like Cells
(2012)The intervertebral discs (IVD) contribute to structural stability of the spinal column, attenuate the impact of compressive loads, and enable a wide spectrum of motions. As a consequence of aging, the majority of the adult ... -
Laminin-Functionalized Polyethylene Glycol Hydrogels for Nucleus Pulposus Regeneration
(2013)Intervertebral disc (IVD) disorders and age-related degeneration are believed to contribute to low back pain. There is significant interest in cell-based strategies for regenerating the nucleus pulposus (NP) region of the ... -
The Effect of Entrapped Laminin-111 in Three-dimensional Polyethylene Glycol Gels on the Behavior of Nucleus Pulposus Cells from the Intervertebral Disc
(2010)The intervertebral disc (IVD) is a fibro-cartilaginous tissue that supports and distributes loads applied to the spine. The two main tissues types of the IVD are the anulus fibrosus (AF), which is comprised of highly organized ... -
The Effects of Extracellular Matrix Mechanics and Composition on the Behaviors of Nucleus Pulposus Cells from the Intervertebral Disc
(2009)Intervertebral disc (IVD) disorders are a major contributor to disability and health costs. Disc disorders and resulting pain may be preceded by changes which first occur in the nucleus pulposus (NP) region of the IVD, ...
