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Browsing by Subject "optogenetics"
Now showing items 1-8 of 8
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A wirelessly controlled implantable LED system for deep brain optogenetic stimulation.
(Front Integr Neurosci, 2015)In recent years optogenetics has rapidly become an essential technique in neuroscience. Its temporal and spatial specificity, combined with efficacy in manipulating neuronal activity, are especially useful in studying the ... -
General Anesthetics Activate a Central Pain-Suppression Circuit in the Amygdala
(2020)General anesthesia (GA) can produce analgesia (loss of pain) independent of inducing loss of consciousness, but the underlying mechanisms remain unclear. We hypothesized that GA suppresses pain in part by activating supraspinal ... -
Genetically Encoded Photoactuators and Photosensors for Characterization and Manipulation of Pluripotent Stem Cells.
(Theranostics, 2017)Our knowledge of pluripotent stem cell biology has advanced considerably in the past four decades, but it has yet to deliver on the great promise of regenerative medicine. The slow progress can be mainly attributed to our ... -
Light-Inducible Gene Regulation in Mammalian Cells
(2015)The growing complexity of scientific research demands further development of advanced gene regulation systems. For instance, the ultimate goal of tissue engineering is to develop constructs that functionally and morphologically ... -
Stimulation of GABAergic neurons of the lateral septum and its effect on movement speed
(2016-06-06)The lateral septum is associated with the regulation of innate behavior, motivation, and locomotion. Its complex interconnections with cognitive and affective regions such as the hippocampus, hypothalamus, and medial septum ... -
The Cellular Determinants of Spinal and Peripheral Pain Processing
(2018)Chronic pain is a major public health issue, affecting over 100 million people in costing over $600 million annually in the United States. The lack of effective therapies for chronic pain have directly contributed to the ... -
Using Light to Control Protein-Protein Interactions: Optogenetics in Drosophila melanogaster
(2016-04-23)Recent advancements in genetically encoded light-sensitive protein systems, also known as optogenetic systems, have stemmed from the many benefits of using blue light stimuli to selectively initiate protein-protein interactions. ...
