Browsing by Subject "polarity"
Now showing items 1-4 of 4
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Cell Polarity Establishment in the Budding Yeast Saccharomyces Cerevisiae
(2009)Establishing an axis of cell polarity is central to cell motility, tissue morphogenesis, and cell proliferation. A highly conserved group of polarity regulators is responsible for organizing a wide variety of polarized ... -
Experimentally informed bottom-up model of yeast polarity suggests how single cells respond to chemical gradients
(2021)How do single cells—like neutrophils, amoebae, neurons, yeast, etc.—grow or move in a directed fashion in response to spatial chemical gradients? To address this question, we used the mating response in the budding yeast, ... -
Mechanisms of Gradient Tracking During Yeast Mating
(2012)Many cells are remarkably proficient at tracking even shallow chemical gradients, despite tiny differences in receptor occupancy across the cell. Stochastic receptor-ligand interactions introduce considerable noise ... -
Parallel Actin-Independent Recycling Pathways Polarize Cdc42 in Budding Yeast.
(Curr Biol, 2016-08-22)The highly conserved Rho-family GTPase Cdc42 is an essential regulator of polarity in many different cell types. During polarity establishment, Cdc42 becomes concentrated at a cortical site, where it interacts with downstream ...
