Browsing by Subject "proteomics"
Now showing items 1-5 of 5
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Characterization of Basal Endfeet Reveals Roles for Local Gene Regulation in Radial Glia and Cortical Development
(2023)Radial glial cells (RGCs) are essential for the generation and organization of neurons in the cerebral cortex. RGCs have an elongated bipolar morphology with basal and apical endfeet that reside in distinct niches. Yet, ... -
Cytoskeletal Networks Driving Presynaptic Plasticity
(2021)Synapses – the delicate connections between our neurons – adjust and refine their strength to shape our brains, our thoughts, and our memories. Proteomic and genetic techniques have revealed that this process, known as synaptic ... -
Detection of Alternative Splice Variants at the Proteome Level in Aspergillus flavus
(2010)Identification of proteins from proteolytic peptides or intact proteins plays an essential role in proteomics. Researchers use search engines to match the acquired peptide sequences to the target proteins. However, search ... -
Elucidating the Molecular Composition of Cartilage by Proteomics.
(J Proteome Res, 2016-02-05)Articular cartilage consists of chondrocytes and two major components, a collagen-rich framework and highly abundant proteoglycans. Most prior studies defining the zonal distribution of cartilage have extracted proteins ... -
Glucocorticoids Preferentially Influence Expression of Nucleoskeletal Actin Network and Cell Adhesive Proteins in Human Trabecular Meshwork Cells.
(Frontiers in cell and developmental biology, 2022-01)Clinical use of glucocorticoids is associated with increased intraocular pressure (IOP), a major risk factor for glaucoma. Glucocorticoids have been reported to induce changes in actin cytoskeletal organization, cell adhesion, ...