Browsing by Subject "radiation therapy"
Now showing items 1-13 of 13
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A current perspective on stereotactic body radiation therapy for pancreatic cancer.
(Onco Targets Ther, 2016)Pancreatic cancer is a formidable malignancy with poor outcomes. The majority of patients are unable to undergo resection, which remains the only potentially curative treatment option. The management of locally advanced ... -
Consensus Segmentation for Positron Emission Tomography: Development and Applications in Radiation Therapy
(2013)The use of positron emission tomography (PET) in radiation therapy has continued to grow, especially since the development of combined computed tomography (CT) and PET imaging system in the early 1990s. Today, the biggest ... -
Dosimetric and radiobiological fitting of xerostomia and dysphagia 12 months after treatment for head and neck tumors
(2018)Oropharyngeal Squamous Cell Carcinoma (OPSCC) is by far the most predominant form of head and neck cancer in the United States. The survival rate for OPSCC is very high, which, while fortunate, yields many patients who are ... -
Improved Pre-clinical Radiation Treatment Techniques for a Novel Mouse Model of Head-and-neck Cancer
(2019)Mice are the predominant animal model used in radiation therapy research for investigating radiobiological kinetics and evaluating new therapeutics to achieve a higher therapeutic ratio in the clinic. A novel carcinogen-induced ... -
Incorporating Case-Based Reasoning for Radiation Therapy Knowledge Modeling: A Pelvic Case Study.
(Technology in cancer research & treatment, 2019-01)Knowledge models in radiotherapy capture the relation between patient anatomy and dosimetry to provide treatment planning guidance. When treatment schemes evolve, existing models struggle to predict accurately. We propose ... -
Investigation of Presage 3D Dosimetry as a Method of Clinically Intuitive Quality Assurance and Comparison to a Semi-3D Delta4 System
(2015)The need for clinically intuitive metrics for patient-specific quality assurance in radiation therapy has been well-documented (Zhen, Nelms et al. 2011). A novel transform method has shown to be effective at converting ... -
On-board Single Photon Emission Computed Tomography (SPECT) for Biological Target Localization
(2010)On-board imaging is useful for guiding radiation to patients in the treatment position; however, current treatment-room imaging modalities are not sensitive to physiology - features that may differentiate tumor from nearby ... -
Predicting 3-D Deformation Field Maps (DFM) based on Volumetric Cine MRI (VC-MRI) and Artificial Neural Networks for On-board 4D Target Tracking
(2019)Organ and tumor positions are constantly subject to change due to involuntary movement from the gastrointestinal and respiratory systems. In radiation therapy, accurate and precise anatomical localization is critical for ... -
Prediction of Electron Cutout Factors Using Residual Neural Network
(2019)AbstractBackground: Monte Carlo and square root are two commonly used calculation methods to predict electron cutout factors in clinic. Monte Carlo is accurate but time consuming, while square root is faster but less accurate ... -
Radiation therapy for primary cutaneous γδ T-cell lymphoma: Case report and literature review.
(JAAD case reports, 2019-07) -
Real-time Target Tracking in Fluoroscopy Imaging using Unet with Convolutional LSTM
(2020)Target localization precision is crucial for the treatment outcome of radiation therapy. In lung stereotatic body radiation therapy (SBRT), verifying target motion in the real time 2D fluoro images is often used as a vital ... -
Targeting cell surface-associated GRP78 enhances pancreatic cancer radiosensitivity by reducing YAP/TAZ protein signaling.
(The Journal of biological chemistry, 2019-07-29)Ionizing radiation (IR) can promote migration and invasion of cancer cells, but the basis for this phenomenon has not been fully elucidated. IR increases expression of glucose-regulated protein 78kDa (GRP78) on the surface ... -
Validation of the dosimetry for a Lay-down Total Skin Irradiation techniques by Monte Carlo Simulation
(2019)Total skin irradiation (TSI) with electron beam has been very effective for patient with Mycosis fungoides. We recently developed and implemented a technique of laying down position for patients who are too frail for the ...
