Browsing by Subject "reactive oxygen species"
Now showing items 1-5 of 5
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Cervical Vagus Nerve Stimulation Improves Neurologic Outcome After Cardiac Arrest in Mice by Attenuating Oxidative Stress and Excessive Autophagy.
(Neuromodulation : journal of the International Neuromodulation Society, 2022-04)<h4>Background</h4>Cerebral ischemia and reperfusion (I/R) induces oxidative stress and activates autophagy, leading to brain injury and neurologic deficits. Cervical vagus nerve stimulation (VNS) increases cerebral blood ... -
Drebrin attenuates atherosclerosis by limiting smooth muscle cell transdifferentiation.
(Cardiovascular research, 2021-04-29)<h4>Aims</h4>The F-actin-binding protein Drebrin inhibits smooth muscle cell (SMC) migration, proliferation and pro-inflammatory signaling. Therefore, we tested the hypothesis that Drebrin constrains atherosclerosis.<h4>Methods ... -
Ornithine Lipids in Burkholderia spp. Pathogenicity.
(Frontiers in molecular biosciences, 2020-01)The genus Burkholderia sensu lato is composed of a diverse and metabolically versatile group of bacterial species. One characteristic thought to be unique for the genus Burkholderia is the presence of two forms each (with ... -
Oxidative Stress and Thrombosis during Aging: The Roles of Oxidative Stress in RBCs in Venous Thrombosis.
(International journal of molecular sciences, 2020-06-15)Mid-life stage adults are at higher risk of developing venous thrombosis (VT)/thromboembolism (VT/E). Aging is characterized by an overproduction of reactive oxygen species (ROS), which could evoke a series of physiological ... -
The Role of RBC Oxidative Stress in Sickle Cell Disease: From the Molecular Basis to Pathologic Implications.
(Antioxidants (Basel, Switzerland), 2021-10)Sickle cell disease (SCD) is an inherited monogenic disorder and the most common severe hemoglobinopathy in the world. SCD is characterized by a point mutation in the β-globin gene, which results in hemoglobin (Hb) S production, ...