Browsing by Subject "single nucleotide polymorphism"

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Genetic variants of genes in the NER pathway associated with risk of breast cancer: A large-scale analysis of 14 published GWAS datasets in the DRIVE study.

Wei, Qingyi; Luo, Sheng; Moorman, Patricia; Ge, Jie; Liu, Hongliang; Qian, Danwen; Wang, Xiaomeng; ... (8 authors) (International journal of cancer, 2019-09)

A recent hypothesis-free pathway-level analysis of genome-wide association study (GWAS) datasets suggested that the overall genetic variation measured by single nucleotide polymorphisms (SNPs) in the nucleotide excision ...
Potential Functional Variants in SMC2 and TP53 in the AURORA Pathway Genes and Risk of Pancreatic Cancer.

Abbruzzese, James; Walsh, Kyle; Wei, Qingyi; Feng, Yun; Liu, Hongliang; Duan, Bensong; Liu, Zhensheng; ... (8 authors) (Carcinogenesis, 2019-02-22)

The AURORA pathway participates in mitosis and cell division, and alterations in mitosis and cell division can lead to carcinogenesis. Therefore, genetic variants in the AURORA pathway genes may be associated with susceptibility ...