Browsing by Subject "traumatic brain injury"
Now showing items 1-12 of 12
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A Feasibility Study of Noninvasive Intracranial Pressure Monitoring for Adults After Traumatic Brain Injury in Uganda
(2022)Introduction: Traumatic brain injury (TBI) accounts for the majority of Uganda’s neurosurgical disease burden, but invasive intracranial pressure (ICP) monitoring is infrequently used. Noninvasive monitoring through tools ... -
A High-Tech Solution for the Low Resource Setting: A Tool to Support Decision Making for Patients with Traumatic Brain Injury
(2019)Background. The confluence of a capacity-exceeding disease burden and persistent resource shortages have resulted in traumatic brain injury’s (TBI) devastating impact in low and middle income countries (LMIC). Lifesaving ... -
Association of Early Beta-Blocker Exposure and Functional Outcomes in Critically Ill Patients With Moderate to Severe Traumatic Brain Injury: A Transforming Clinical Research and Knowledge in Traumatic Brain Injury Study.
(Critical care explorations, 2023-09)<h4>Objectives</h4>We aimed to 1) describe patterns of beta-blocker utilization among critically ill patients following moderate-severe traumatic brain injury (TBI) and 2) examine the association of early beta-blocker exposure ... -
Brain Natriuretic Peptide Improves Long-Term Functional Recovery after Acute CNS Injury in Mice
(2010-01)There is emerging evidence to suggest that brain natriuretic peptide (BNP) is elevated after acute brain injury, and that it may play an adaptive role in recovery through augmentation of cerebral blood flow (CBF). Through ... -
Engineering Cytokine and Macrophage Enrichment at Sites of Injury
(2019)Appropriately modulating inflammation after traumatic brain injury (TBI) may prevent disabilities in the millions that suffer TBI every year. Important mediators of inflammation include macrophages and microglia and these ... -
Epidemiology and Outcomes of Acute Respiratory Distress Syndrome Following Isolated Severe Traumatic Brain Injury.
(Journal of intensive care medicine, 2020-11-15)Patients with traumatic brain injury (TBI) are at risk for extra-cranial complications, such as the acute respiratory distress syndrome (ARDS). We conducted an analysis of risk factors, mortality, and healthcare utilization ... -
Epidemiology and Predictors of Mortality of Traumatic Brain Injury at Kigali University Teaching Hospital Accident and Emergency Department
(2015)Background:Traumatic Brain Injury (TBI) is a leading cause of death and disability. TBI patients in low and middle- income countries (LMIC) have twice the odds of death than in high-income countries. There is limited data ... -
Geographic Disparities in Mortality Risk Within a Racially Diverse Sample of U.S. Veterans with Traumatic Brain Injury.
(Health Equity, 2018-01)Purpose: Traumatic brain injury (TBI) is a signature injury among the U.S. veterans. Hispanic U.S. veterans diagnosed with TBI have been found to have higher risk-adjusted mortality. This study examined the adjusted association ... -
Management of Severe Traumatic Brain Injury in Pediatric Patients.
(Frontiers in toxicology, 2022-01)The optimal management of severe traumatic brain injury (TBI) in the pediatric population has not been well studied. There are a limited number of research articles studying the management of TBI in children. Given the prevalence ... -
Racial and Ethnic Differences in the Prevalence of Do-Not-Resuscitate Orders among Older Adults with Severe Traumatic Brain Injury.
(Journal of intensive care medicine, 2022-05-22)<h4>Background</h4>Older adults suffering from traumatic brain injury (TBI) are subject to higher injury burden and mortality. Do Not Resuscitate (DNR) orders are used to provide care aligned with patient wishes, but they ... -
The Impact of Care Delays on Traumatic Brain Injury Outcomes in Tanzania: Descriptive Analytics and Machine Learning
(2020)Background: Traumatic brain injury (TBI) is the leading cause of trauma related death and disability worldwide. Poor TBI outcomes disproportionately affect low- and middle-income countries (LMICs). Treatment delays may contribute ... -
Transferring and Adapting a Prognostic Model to Improve Care of Brazilian Traumatic Brain Injury Patients
(2020)AbstractBackground: Traumatic brain injury (TBI) is a major cause of death and disability. About 10 million people annually are affected by TBI, with a prominent burden in low- and middle-income countries (LMICs). In Brazil, ...