Now showing items 1-2 of 2

    • Complex Role for E-Prostanoid 4 Receptors in Hypertension. 

      Herrera, Marcela; Yang, Ting; Sparks, Matthew A; Manning, Michael W; Koller, Beverly H; Coffman, Thomas M (Journal of the American Heart Association, 2019-02)
      Background Prostaglandin E2 ( PGE 2) is a major prostanoid with multiple actions that potentially affect blood pressure ( BP ). PGE 2 acts through 4 distinct E-prostanoid ( EP ) receptor isoforms: EP 1 to EP 4. The EP 4 ...
    • Drebrin attenuates atherosclerosis by limiting smooth muscle cell transdifferentiation. 

      Wu, Jiao-Hui; Zhang, Lisheng; Nepliouev, Igor; Brian, Leigh; Huang, Taiqin; Snow, Kamie P; Schickling, Brandon M; ... (11 authors) (Cardiovascular research, 2021-04-29)
      <h4>Aims</h4>The F-actin-binding protein Drebrin inhibits smooth muscle cell (SMC) migration, proliferation and pro-inflammatory signaling. Therefore, we tested the hypothesis that Drebrin constrains atherosclerosis.<h4>Methods ...