Browsing Theses and Dissertations by Title
Now showing items 4622-4641 of 6862
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On the Functions of Morality
(2015)This dissertation seeks to bring together two philosophical literatures: the functions literature from the philosophy of biology, and the functionalist literature in naturalistic metaethics. Biological function suggests ... -
On the Horizontal Advection and Biogeochemical Impacts of North Atlantic Mode Waters and Boundary Currents
(2007-07-26)Using a combination of hydrographic data and the trajectories and profiles of isobaric floats, this dissertation evaluates the connections between remote regions in the North Atlantic. First, I establish that the production ... -
On the Love of God
(2015)AbstractThis dissertation queries the ongoing significance and fruitfulness of Augustine of Hippo's insight that the Holy Spirit is the Love of God. Rather than turning to the standard text, his De Trinitate, this project ... -
On the Origin of Natural Antibody
(2016)Natural IgM (nIgM) is constitutively present in the serum, where it aids in the early control of viral and bacterial expansions. nIgM also plays a significant role in the prevention of autoimmune disease by promoting the ... -
On the Regulation of Small Actors: Three Experimental Essays about Policies based on Voluntary Compliance and Decentralized Monitoring
(2016)Monitoring and enforcement are perhaps the biggest challenges in the design and implementation of environmental policies in developing countries where the actions of many small informal actors cause significant impacts on ... -
On Uncertainty Quantification for Systems of Computer Models
(2017)Scientific inquiry about natural phenomena and processes are increasingly relying on the use of computer models as simulators of such processes. The challenge of using computer models for scientific investigation is that ... -
On-Board Imaging of Respiratory Motion: Investigation of Markerless and Self-Sorted Four-Dimensional Cone-Beam CT (4D-CBCT)
(2013)To date, image localization of mobile tumors prior to radiation delivery has primarily been confined to 2D and 3D technologies, such as fluoroscopy and 3D cone-beam CT (3D-CBCT). Due to the limited information from these ... -
On-board Robotic Multi-pinhole SPECT System for Region-of-interest (ROI) Imaging
(2014)On-board image guidance, such as cone-beam CT (CBCT) and kV/MV 2D imaging, is essential in many radiation therapy procedures, such as intensity modulated radiotherapy (IMRT) and stereotactic body radiation therapy (SBRT). ... -
On-board Single Photon Emission Computed Tomography (SPECT) for Biological Target Localization
(2010)On-board imaging is useful for guiding radiation to patients in the treatment position; however, current treatment-room imaging modalities are not sensitive to physiology - features that may differentiate tumor from nearby ... -
An on-campus community grocery store: A social purpose business model for Paul Quinn College
(2013-04-19)EXECUTIVE SUMMARY Paul Quinn College (PQC) has a vision for becoming an engine for economic and social change in the community, transforming the lives of residents in PQC’s under-resourced neighborhood while providing ... -
On-chip Labeling via Surface Initiated Enzymatic Polymerization (SIEP) for Nucleic Acids Hybridization Detection
(2013)Current techniques for nucleic acid analysis often involve extensive sample preparation that requires skilled personnel and multiple purification steps. In this dissertation, we introduce an on-chip, isothermal, ... -
Oncogenic KRAS Expression and Signaling
(2012)RAS is a small GTPase that helps to convert extracellular cues into intracellular actions. It is the most commonly mutated oncogene and is found in an active mutant form in 90% of pancreatic cancers. Therefore, study of ... -
One Gene or Many? Different Genetic Mechanisms Drive Convergent Evolution in Monkey Flowers
(2016-04-24)Evolutionary history is riddled with examples of convergent evolution, in which the same adaptation appears independently across multiple populations as a result of similar selective pressures. Convergent evolution can ... -
A One Health Perspective on Disease Dynamics: Human Monkeypox Transmission in Sankuru District, Democratic Republic of Congo
(2015)Background: Reports from the first monkeypox (MPX) active surveillance program in the Democratic Republic of Congo (DRC) in the 1980s determined that the disease was not of epidemic potential, with R0<1. However, during ... -
Online Auction Markets
(2009)Central to the explosive growth of the Internet has been the desireof dispersed buyers and sellers to interact readily and in a mannerhitherto impossible. Underpinning these interactions, auctionpricing mechanisms have ... -
Online Learning of Non-Stationary Networks, with Application to Financial Data
(2012)In this paper, we propose a new learning algorithm for non-stationary Dynamic Bayesian Networks is proposed. Although a number of effective learning algorithms for non-stationary DBNs have previously been proposed and ... -
Ontogeny of Lower Limb Morphology and Proportions in the Dinaledi Hominins
(2015)The discovery of hundreds of fossil hominin remains from the Dinaledi Chamber of Rising Star cave in South Africa included dozens of immature elements attributed to multiple individuals. Some of these elements are amongst ... -
The Ontogeny of Mucosal and Systemic Antibody Responses to HIV-1 Infection
(2014)The humoral immune system plays a critical role in the clearance of numerous pathogens. In the setting of HIV-1 infection, the virus infects, integrates its genome into the host's cells, replicates, and establishes a ... -
Opening Basement Membrane Gaps During C. elegans Uterine-Vulval Attachment
(2016)The basement membrane (BM) is a highly conserved form of extracellular matrix that underlies or surrounds and supports most animal tissues. BMs are crossed by cells during various remodeling events in development, immune ... -
Opening Duke University’s Energy Data
(2013-04-26)Duke University stores and maintains a variety of data regarding energy and water consumption on its campuses. These data have traditionally been known to and accessible only by Duke's Facilities Management Department ...
