Now showing items 1-10 of 19
Optimized approach to decision fusion of heterogeneous data for breast cancer diagnosis.
(Med Phys, 2006-08)
As more diagnostic testing options become available to physicians, it becomes more difficult to combine various types of medical information together in order to optimize the overall diagnosis. To improve diagnostic performance, ...
Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation.
(J Clin Invest, 2011-03)
Allergic asthma is characterized by airway hyperresponsiveness, inflammation, and a cellular infiltrate dominated by eosinophils. Numerous epidemiological studies have related the exacerbation of allergic asthma with an ...
Distinct functions of POT1 at telomeres.
(Mol Cell Biol, 2008-09)
The mammalian protein POT1 binds to telomeric single-stranded DNA (ssDNA), protecting chromosome ends from being detected as sites of DNA damage. POT1 is composed of an N-terminal ssDNA-binding domain and a C-terminal protein ...
Comparative performance of multiview stereoscopic and mammographic display modalities for breast lesion detection.
(Med Phys, 2011-04)
PURPOSE: Mammography is known to be one of the most difficult radiographic exams to interpret. Mammography has important limitations, including the superposition of normal tissue that can obscure a mass, chance alignment ...
Pharmacological targeting of the mitochondrial phosphatase PTPMT1.
(J Pharmacol Exp Ther, 2010-05)
The dual-specificity protein tyrosine phosphatases (PTPs) play integral roles in the regulation of cell signaling. There is a need for new tools to study these phosphatases, and the identification of inhibitors potentially ...
Prostate Bed Motion During Post-Prostatectomy Radiotherapy
(MEDICAL PHYSICS, 2012-06)
A novel, non-apoptotic role for Scythe/BAT3: a functional switch between the pro- and anti-proliferative roles of p21 during the cell cycle.
(PLoS One, 2012)
BACKGROUND: Scythe/BAT3 is a member of the BAG protein family whose role in apoptosis has been extensively studied. However, since the developmental defects observed in Bat3-null mouse embryos cannot be explained solely ...
Characterization of Image Quality for 3D Scatter Corrected Breast CT Images.
(Proc SPIE Int Soc Opt Eng, 2011-03-16)
The goal of this study was to characterize the image quality of our dedicated, quasi-monochromatic spectrum, cone beam breast imaging system under scatter corrected and non-scatter corrected conditions for a variety of breast ...
Plate-specific gain map correction for the improvement of detective quantum efficiency in computed radiography.
(Med Phys, 2012-03)
PURPOSE: The purpose of this work is to improve the noise power spectrum (NPS), and thus the detective quantum efficiency (DQE), of computed radiography (CR) images by correcting for spatial gain variations specific to individual ...
Mechanisms of specificity in neuronal activity-regulated gene transcription.
(Prog Neurobiol, 2011-08)
The brain is a highly adaptable organ that is capable of converting sensory information into changes in neuronal function. This plasticity allows behavior to be accommodated to the environment, providing an important evolutionary ...