Now showing items 1-6 of 6
Linking WRP/srGAP3 to the Cognitive Deficits in 3p- Syndrome and Its Role in the Regulation of Dendritic Filopodia Formation
Rho GTPase signaling regulates a wide variety of cellular functions in the developing and adult central nervous system. These molecular switches are in turn spatially and temporally regulated by an over abundance of positive ...
The Role of Caveolin-1 and Surfactant Protein A as Regulators of Airway Hyperreactivity and Inflammation Following Innate Immune Challenges
The lung is a unique organ, taking a key part physiology but also playing a vital role in host defense. The lung has therefore developed a complex innate immune system that includes ciliated mucus producing cells that trap ...
Novel Roles for Desmosomes in Cytoskeletal Organization
Microtubules often adopt non-centrosomal arrays in differentiated tissues, where they are important for providing structure to the cell and maintaining polarity. Although the formation and organization of centrosomal arrays ...
Microtubule Severing Protein Regulation of Sensory Neuron Form and Function in Drosophila melanogaster
Dendrite shape is a defining component of neuronal function. Yet, the mechanisms specifying diverse dendritic morphologies, and the extent to which their functioning depends on these morphologies, remain unclear. Here, we ...
Fibroblasts as a Window into the Cell Biology of Ankyrin -B and -G
The ankyrin family of proteins form specialized membrane domains in various cell types, including neurons and cardiomyocytes but little is known about how this process occurs. The majority of ankyrins localize to the plasma ...
Understanding Cell Fate Decisions in the Embryonic Gonad
The divergence of distinct cell populations from multipotent progenitors is poorly understood, particularly <italic>in vivo</italic>. The gonad is an ideal place to study this process because it originates as a bipotential ...